Effect of isolated fatty acids from flaxseeds Linumusitatissimum against LeishmaniatropicaIn vitro

1Dr. Hasan Mohammed Hasan

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Abstract:

The current study aimed to test the effectiveness of Fatty acid separated from the seeds of the flax plant Linum usitatissimum on the parasite Leishmaniatropica. Palmatic acid, Steric acid, Olic acid, Arachidic acid, Behenic acid). These fatty acids were used as a possible antilieshmanial agents in vitro, as the results showed that the concentration of 100 μg/ml gave a complete inhibition of the parasite’s growth in the promastigote form in 48 hours and up by 100% compared to the control group which The growth of the parasite was witnessed at all times, while the concentration of 25 μg/ml showed a decrease in the percentage of inhibition compared to the rest of the concentrations, which was 78.8% at the time of 96 hours, and the inhibitory concentration for 90% of the parasites (LC90)) was at the concentration of 50 μg/ml. milliliters at log phase 96 hours of culture. This led to a reduction in the number of generations and an increase in the time required to produce them compared to the control group.

Keywords:

Fatty acid, flax, Linumusitatissimum, Leishmaniatropica.fatty acids

Paper Details
Month3
Year2021
Volume25
IssueIssue 3
Pages1382-1396