Soluble Transferrin Receptor-Ferritin Indices as Diagnostic Tool for Iron Deficiency Anemia in Chronic Kidney Disease in Children

1Hatem Mohamed Hussein, EzzatKamel Amin, Naglaa Ali Khalifa, Esraa Khalid Hassan

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Abstract:

Background: Chronic kidney disease is an important chronic, non-communicable epidemic disease. Up to 80% of patients with Chronic kidney disease may have anaemia. Soluble serum transferrin receptor (sTfR) was introduced as a promising new diagnostic tool of iron status. The main objective of this study was to assess the utility of soluble transferrin receptor-Ferritin Indices as markers of iron deficiency anemia in chronic kidney disease patient. Methods: This was a cross-sectional study was conducted at Department of Pediatric Nephrology at Zagazig University Hospital including 45 anemic children. The duration of the study ranges from 6 to 12 months. Soluble serum transferrin receptor and Soluble serum transferrin receptor index were measured. Results: There was no significant difference among groups regard age or BMI distribution. There was no significant difference regard sex distribution among studied groups. regard s TIR and s TIR index IDA group were significantly higher than other two groups then mixed and finally ACD were significantly lower. Conclusion: Soluble transferrin receptor value was useful tool for assessment of iron status in patients with CKD.

Keywords:

Soluble transferrin receptor- assessment- anemia-CKD.

Paper Details
Month12
Year2020
Volume24
IssueIssue 10
Pages6555-6562