RECENT ADVANCES IN THE TREATMENT OF HIV INFECTION-A REVIEW

1Akshaya A, A. Jothipriya, K. R. Don

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Abstract:

HIV is the leading cause for mortality and morbidity across worldwide. HIV infection is considered as medical apocalypse in certain age period, because it caused massive infection spread .However many interpretations and inventions in the treatment of HIV infection, it is still been considered as major disease burden, because it affects directly the immune cells of individuals and make them more vulnerable to common infections.Advances in HIV / AIDS therapy were quick and well-exposed. An improved understanding of HIV pathogenesis has shown the need for aggressive antiretroviral therapy in most HIV-infected people. At least three combinations of drugs are needed to suppress viral replications. In addition, the capacity of pharmaceutical firms to formulate such effective medications into fixed-dose formulations offers innovative new pill stress reduction techniques, thus ensuring adherence and reducing the development of drug-resistance.However, the excitement with which these new drugs were greeted has been tempered by the fact of restricted access in the developing world, further illustrating the gap in the battle against HIV / AIDS between the rich and poor countries. Such therapies would require proper political will and medication access to low and middle income countries. Developing countries' goal continues to increase the scope of ART, but in order to tackle toxicity and drug resistance, both of which threaten the viability of these initiatives, new drugs are also required. Nowadays recent studies focus on obtaining viral sequences found in newly infected individuals to identify and examine the features of all transmitted pathogens which could provide potential targets to develop HIV vaccine. This study focuses on mainly the recent advanced methodologies used in HIV treatment.

Keywords:

HIV infection, CCR5 protein, Nucleotide reverse transcriptase inhibitors, Non-nucleotide reverse transcriptase inhibitors, Replication.

Paper Details
Month3
Year2020
Volume24
IssueIssue 3
Pages5237-5243