A prospective clinicopathological study on multinodular goiter in Iraqi patients

1Mohammed Mohammud Habash

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Abstract:

Background Thyroid gland is a shield considered to protect the larynx and plays very important functions in the body. Thyroid swellings and enlargement are commonly encountered in clinical findings and surgical practice. Thyroid enlargement with formation of multiple distinct nodules are characteristics of Multinodular goiter (MNG). Iodine deficiency leads to increase in the thyroid stimulating hormone (TSH). Thus, prolonged stimulation by elevated TSH may develop MNG and more prone to malignant transformation. Present study was planned to study clinicopathological aspect of MNG with respect to TSH hormone levels in Iraqi patients Method The present study was a hospital-based prospective study conducted in Al - Shafa hospital, Diyala, Iraq between January 2018 to January 2020. 41 patients aged between 15 to 75 yrs. Clinically diagnosed as multinodular goiter (MNG) were included in the study. Result In the present study, all the recruited patients are having swelling in the anterior side of the neck. Minimum age recorded in both the genders was 22 years. While maximum age in male was 60 years and in female it was 78 years, thus total mean age was 45.5 years. Of the 40 patients, majority of cases were female that is 34 patients and remaining 6 cases were males, having sex ratio of female to male 17:3. Total thyroidectomy was performed, and histopathology study was carried out to check the malignancy. Inference In our study, we have found the pathological presentation of goiter is benign and clinically swelling of the neck is observed. The majority of females were affected by MNG. Total thyroidectomy was the preferred method for the malignant cases over other types of surgeries.

Keywords:

Goiter, Multinodular, thyroid stimulating hormone, malignancy

Paper Details
Month7
Year2020
Volume24
IssueIssue 5
Pages8046-8052