The Correlation between Anti-Mullerian Hormone Levels and The Number of Oocyte Retrieved and Pregnancy Rate in Infertile Women Who Underwent IVF in Makassar City

1Arini Estiastuti, Nusratuddin Abdullah, Rudy Butje Leonardy

206 Views
65 Downloads
Abstract:

Anti-Mullerian hormone (AMH) being a good marker for ovarian response. Decrease serum AMH levels may be indicative for poor response in vitro fertilization (IVF) in women with a diminished ovarian reserve This study aims to determine the serum level of AMH correlation with the number of oocyte retrieved and pregnancy rate in infertile women. This cross-sectional study was eligible for 254 infertile women underwent in vitro fertilization in private IVF Clinic in Makassar. AMH serum levels were measured on cycle day 3. The number of oocytes were determined on the day of oocyte retrieval. Pregnancy was determined by the βhCG test on day 16 of the cycle. Serum AMH levels show a significant negative correlation with women <35 years (r=-0.178; p=0.029) and a negative correlation but not significant with women age ≥35 years (r=-0.144; p=0.144). Conversely, AMH levels and the number of oocyte retrieved show a significant positive correlation (r=0.507, p=0.000). Chemical pregnancy does not correlate with AMH levels (p>.05). The AMH levels and the number of oocytes retrieved might predict the ovarian function. AMH levels could not predict the pregnancy rates.

Keywords:

AMH, oocyte, pregnancy rate, IVF

Paper Details
Month3
Year2020
Volume24
IssueIssue 3
Pages3870-3874