Catalogue of Cancer Genes – The First Step to Winning the Fight against Cancer

1Dmitry V. Karpov, Lyubov I. Karpova, Ilya I. Vinogradov and Sergey V. Dmitrienko

213 Views
50 Downloads
Abstract:

Performance of an important task of creating a detailed catalogue of cancer genes will allow to select an optimal cancer therapy for each patient. To catalogue cancer genes, mutating with high (>20%) and medium (2–20%) frequency, 200 “tumour-norm” pairs on average for each gene should be analysed, i.e. about 100000 pairs for the most common types of cancer. Nowadays, the problem is no longer insoluble, since the cost of DNA sequencing has decreased a million fold over the last 10 years and will continue to decrease more.

Keywords:

Sequencing, Cancer, Proto-oncogene, Anti-oncogene, Cancer Genome Atlas.

Paper Details
Month4
Year2020
Volume24
IssueIssue 5
Pages4900-4905