Detection of Human Herpes Virus-6 in Children Suffering from Febrile Convulsion

1Jwan A. Ali*, Zaytoon A.R. Al-Kafaji and Adnan H. Al-Jothery

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Abstract:

A total of (150) blood samples were taken from children who suffering from febrile convulsion, during the period from April (2019) to October (2019), who admitted to Babel Hospital, Al-Noor Hospital and Al- Imam Al-Sadiq Center, at age range from six month to five years old. out of (150) blood samples, (50) samples of children who suffering from febrile convulsion fit as group one [31 male (62%) and 19 female (38%)], (50) samples of children who suffering from fever without fit as group two [34 male (68%) and 16 female (32%)] and (50) samples of control case (healthy children) as group three [male 36 (72%) and 14 female (28%).Demographic data of patients and control (age, gender, weight and residence) were studied from all blood samples were taken from children. The mean of ages for the three study groups was investigated, it was found that, there were no significant statistical relationship between them (P= 0.88), Distribution of study groups according to gender was studied, the results showed that, They were no important variances among study groups (P= 0.56) regarding gender. According to study patient’s weight, there were no important statistical relationship among the study groups (P= 0.28).In this study, distribution of patient groups according to the residence was studied, it was found that, there were highly significant differences (P= 0.000) in the urban within the health group compared with patients group. Human Herpes Virus 6 was were detection from blood samples by qPCR technique. It was found that, from 50(100%) samples of conventional febrile (fit with fever), 18(36%) isolated were related of HHV6. In group of fever, It was found that, from 50(100%) samples, 12(24%) isolated were related of this virus.

Keywords:

Febrile Convulsion, Human Herpes Virus-6, fit with Fever, PCR.

Paper Details
Month4
Year2020
Volume24
IssueIssue 5
Pages3043-3049