DIAGNOSTIC TEST USING NEUROLOGICAL DEPRESSION DISORDERS INVENTORY FOR EPILEPSY COMPARED TO HAMILTON DEPRESSION RATING SCALE -17 AS A GOLD STANDARD

1Andi Prasetiawan, Kurnia Kusumastuti

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Abstract:

Background Depression is a comorbidity which is most frequently ound in epileptic patients. Epileptic patients have a 5-10 times higher risk to suffer from depression compared to general population.Unfortunately, screening for depression hasn’t been performed routinely in outpatient neurology clinic. Hamilton Depression Rating Scale (HDRS) is a well-known test and often used as a screening instrument, but it spares a lot of time. Objectives To determine the diagnostic value of Using Neurological Depression Disorders Inventory(NDDI)-E compared to the HDRS-17 as a gold standard which was used as a screening instrument to detect the depression inepilepticpatients. Methods This study used cross-sectional design on epileptic patients of the 71 patients neurology clinic and EEG unit Soetomo Teaching Hospital, Surabaya during March to June 2016. the sample in this study that consisting of 37 men and 34 women.The diagnosis of depression was performed using NDDI-E to compared with HDRS-17. Statistical analysis was performed by SPSS16 and cat maker. Results Moreover, from the statistical tests obtained; the mean age was 34.3+12,301 year. Compared with HDRS-17, the Sensitivity value of NDDI-E was 86%,and the specificity value was 72%, positive prediction value was 67%, negative prediction value was 89%, positive probability ratio was 3,07 %, and negative probability ratio was 0,2%. Conclusion NDDI-E could be used as a screening instrument to detect depression in epileptic patients.

Keywords:

Diagnostic Test, Neurological Disorders Depression Inventory for Epilepsy, Hamilton Depression Rating Scale-17

Paper Details
Month2
Year2020
Volume24
IssueIssue 2
Pages4020-4029