Relationship of oxidative enzymes with biochemical parameters in breast cancer patients

1Yogesh Bansal

1Dr. Yogesh Bansal, Department of Biochemistry, Rajshree Medical Research Institute, Bareilly (U.P.)- 243501.

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Abstract:

Background - Breast cancer has a complex aetiology. Significant breast cancer risk factors include age, food, obesity, inactivity, hormone replacement therapy, family history, and others. Our current study's objective was to evaluate the electrolyte and biochemical parameter values in both breast cancer patients and healthy individuals. We have also investigated the link between the antioxidant enzymes and levels of electrolytes. Methods- The data came from 292 individuals who took part in closely supervised clinical research on the correlation between oxidative enzymes and biochemical indicators in breast cancer patients. Finding the connection between biochemical markers and oxidative enzymes in breast cancer patients was the goal of this open, non-randomized study. Results- Aside from albumin, which has significantly increased in the healthy control patients (P = 0.04), no alterations in liver indicators like amylase and glucose were found. The most notable increases in K+, Ca2+, and PO43 were seen in patients with low baseline levels (P = 0.05). In the group of patients with breast cancer, it was also discovered that Na+ and PO43 increased significantly (P = 0.05). Conclusion- Patients with breast cancer had elevated levels of YGT, LDH, ALP, urea, and phosphate, which might be employed as serum indicators for early identification of breast cancer. Antioxidant enzyme levels, on the other hand, were considerably lower in breast cancer patients.

Keywords:

Breast Cancer, Antioxidant Enzymes, Biochemical Parameters, Liver-function enzymes

Paper Details
Month12
Year2019
Volume23
IssueIssue 6
Pages1838-1841

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