STRUCTURAL-MORPHOLOGICAL CHANGES OF BONE TISSUE IN PATIENTS WITH CHRONIC RECURRENT HEMATOGENOUS OSTEOMYELITIS
DOI:
https://doi.org/10.61841/1n4w4j12Keywords:
chronic osteomyelitis, bone tissue, morphologyAbstract
To study the morphological features of the structure of bone tissue in patients with chronic recurrent hematogenous osteomyelitis.The studied material of scanning and transmission electron microscopy were bone fragments of 40 patients obtained during surgery from various pathologically altered sections of the affected tubular bones.Morphological studies revealed microscopic foci of necrosis, leukocyte infiltrates and microabscesses both in the main focus and in other parts of the bone marrow canal.Microabscesses detected by microscopy represent the morphological basis of chronic hematogenous osteomyelitis, can be located at a considerable distance from the main necrotic purulent focus and, under appropriate conditions, cause a relapse of the disease. Morphological studies have shown that surgical debridement of the lesion with ultrasonic cavitation of the lesion and the medullary canal contributes to a significant reduction in the degree of microbial contamination, followed by a decrease in pathological changes in bone tissue.
Downloads
References
1. Akinshina A.D. Comprehensive treatment of chronic osteomyelitis in children, taking into account somatic status. Abstract. dis ... cand. medical science. Moscow. 2017: 24 [
2. Garkavenko Yu.E. Morphological assessment of the effects of hematogenous osteomyelitis of long bones in children // Traumatology and Orthopedics of Russia. 2012; 3: 27-34
3. [Garkavenko YU.Ye. Morfologicheskaya otsenka posledstviy gematogennogo osteomiyelita dlinnykh kostey u detey // Travmatologiya i ortopediya Rossii. 2012; 3: 27-34].
4. Hryhorovskyi V., Hrytsai M.P., Hordii A.S., Hryhorovska A.V. Features of clinical and morphological picture and diagnostics of «atypical forms» of hematogenous osteomyelitis of long bones. Orthopaedics, Traumatology and Prosthetics. 2015;(1):5-11. doi: 10.15674/0030-5987201515-11. (in Ukrainian)
5. Shah K.M. Chronic non-suppurative osteomyelitis with proliferative periostitis or Garre's osteomyelitis /
K.M. Shah, A. Karagir, S. Adaki // BMJ Case Rep.- 2013.- May 13.- doi:pii: bcr2013009859. 10.1136/bcr- 2013-009859.
6. Wang X, Wang Z, Fu J, Huang K, Xie Z. Induced membrane technique for the treatment of chronic hematogenous tibia osteomyelitis. // BMC Musculoskelet Disord. 2017 Jan 23;18(1):33.
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
