EFFECTS OF SMOKING
DOI:
https://doi.org/10.61841/pzcdy184Keywords:
smoking, tobacco, Pre cancerous lesions, Periodontitis, dental cariesAbstract
It is well known that smoking contributes to the development of lung cancer and cardiovascular disease, and there is weighty evidence that it has a considerable influence on oral health. Smoking has many negative effects on the mouth, including staining of teeth and dental restorations, reduction of the ability to smell and taste, and the development of oral diseases such as smoker’s palate, smoker’s melanosis,oral candidiasis and dental caries, periodontal disease, implant failure, oral pre cancer and cancer. From a qualitative point of view the latter is obviously the most serious tobacco-related effect in the mouth. Quantitatively, however, importance has been attached to periodontitis, which affects a large proportion of the population, and during recent years more attention has been given to implant survival rates. As tobacco accounts for such a high proportion of these diseases, comprehensive tobacco control policies are required to make progress in reducing the burden of tobacco-related oral diseases.The present review focuses on smoking‐associated oral health problems in older adults, and the steps required for cessation of the habit. Effective treatments to prevent tobacco use and increase cessation are available and need greater implementation. Dental practices may provide a uniquely effective setting for tobacco prevention and cessation.
Downloads
References
[1] Musk AW, De Klerk NH. History of tobacco and health. Respirology. 2003 Sep;8(3):286-90.
[2] Doll R. Uncovering the effects of smoking: historical perspective. Statistical methods in medical research. 1998 Apr;7(2):87-117.
[3] Adam T, Baker RR, Zimmermann R. Investigation, by single photon ionisation (SPI)–time-of-flight mass spectrometry (TOFMS), of the effect of different cigarette-lighting devices on the chemical composition of the first cigarette puff. Analytical and bioanalytical chemistry. 2007 Jan 1;387(2):575-84.
[4] Hecht SS. Cigarette smoking: cancer risks, carcinogens, and mechanisms. Langenbeck's Archives of Surgery. 2006 Nov 1;391(6):603-13.
[5] Pillai HS, Jagannathan N. Tobacco–A potential threat to the oral cavity.
[6] Ma N, Tagawa T, Hiraku Y, Murata M, Ding X, Kawanishi S. 8-Nitroguanine formation in oral leukoplakia, a premalignant lesion. Nitric oxide. 2006 Mar 1;14(2):137-43.
[7] Bánóczy J, Gintner Z, Dombi C. Tobacco use and oral leukoplakia. Journal of dental education. 2001 Apr 1;65(4):322-7.
[8] Schepman KP, Bezemer PD, Van der Meij EH, Smeele LE, Van Der Waal I. Tobacco usage in relation to the anatomical site of oral leukoplakia. Oral diseases. 2001 Jan;7(1):25-7.
[9] Johnson N, Bain C. Tobacco and oral disease. British Dental Journal. 2000 Aug 26;189(4).
[10] Reibel J. Tobacco and oral diseases. Medical principles and practice. 2003;12(Suppl. 1):22-32.
[11] Saraswathi TR, Ranganathan K, Shanmugam S, Sowmya R, Narasimhan PD, Gunaseelan R. Prevalence of oral lesions in relation to habits: Cross-sectional study in South India. Indian Journal of Dental Research. 2006 Jul 1;17(3):121.
[12] Soysa NS, Ellepola AN. The impact of cigarette/tobacco smoking on oral candidosis: an overview. Oral diseases. 2005 Sep;11(5):268-73.
[13] Yuca K, Calka O, Kiroglu AF, Akdeniz N, Cankaya H. Hairy tongue: a case report. Acta oto-rhino-laryngologica Belgica. 2004;58(4):161-3.
[14] IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, World Health Organization, International Agency for Research on Cancer. Tobacco smoke and involuntary smoking. IARC; 2004.
[15] Williams SA, Kwan SY, Parsons S. Parental smoking practices and caries experience in pre–school children. Caries Research. 2000;34(2):117-22.
[16] Winn DM. Tobacco use and oral disease. Journal of dental education. 2001 Apr 1;65(4):306-12.
[17] Nylander K, Dabelsteen E, Hall PA. The p53 molecule and its prognostic role in squamous cell carcinomas of the head and neck. Journal of Oral Pathology & Medicine: Review article. 2000 Oct;29(9):413-25.
[18] Ravald N, Birkhed D, Hamp SE. Root caries susceptibility in periodontally treated patients: results after 12 years. Journal of clinical periodontology. 1993 Feb;20(2):124-9.
[19] Johnson BD, Engel D. Acute necrotizing ulcerative gingivitis. A review of diagnosis, etiology and treatment. J Periodontol 1986;57:141–50.
[20] Travis J, Pike R, Imamura T, Potempa J. The role of proteolytic enzymes in the development of pulmonary emphysema and periodontal disease. American journal of respiratory and critical care medicine. 1994 Dec 1;150(6):S143.
[21] Bergström J, Preber H. Tobacco use as a risk factor. Journal of periodontology. 1994 May;65(5s):545-50.
[22] Meisel P, Siegemund A, Dombrowa S, Sawaf H, Fanghaenel J, Kocher T. Smoking and polymorphisms of the interleukin-1 gene cluster (IL-1β, IL-1α, and IL-1RN) in patients with periodontal disease. Journal of periodontology. 2002 Jan 1;73(1):27-32.
[23] Axelsson P, Paulartder J, Lindhe J. Relationship between smoking and dental status in 35‐, 50‐, 65‐, and 75‐year‐old individuals. Journal of clinical periodontology. 1998 Apr;25(4):297-305.
[24] Hirsch JM, Livian G, Edward S, Noren JG. Tobacco habits among teenagers in the city of Göteborg, Sweden, and possible association with dental caries. Swedish dental journal. 1991;15(3):117-23.
[25] Jette AM, Feldman HA, Tennstedt SL. Tobacco use: a modifiable risk factor for dental disease among the elderly. American Journal of Public Health. 1993 Sep;83(9):1271-6.
[26] Lie MA, Loos BG, Henskens YM, Timmerman MF, Veerman EC, Velden UV, Weijden GV. Salivary cystatin activity and cystatin C in natural and experimental gingivitis in smokers and non‐smokers. Journal of clinical periodontology. 2001 Oct;28(10):979-84.
[27] Grossi SG, Skrepcinski FB, DeCaro T, Zambon JJ, Cummins D, Genco RJ. Response to periodontal therapy in diabetics and smokers. Journal of periodontology. 1996 Oct;67:1094-102.
[28] Wallace RH. The relationship between cigarette smoking and dental implant failure. The European journal of prosthodontics and restorative dentistry. 2000 Sep;8(3):103-6.
[29] Lindquist LW, Carlsson GE, Jemt T. Association between marginal bone loss around osseointegrated mandibular implants and smoking habits: a 10-year follow-up study. Journal of dental research. 1997 Oct;76(10):1667-74.
[30] Hoffmann DH. The changing cigarette, 1950-1995. Journal of Toxicology and Environmental Health Part A. 1997 Mar 1;50(4):307-64.
[31] Sato K, Endo S, Tomita H. Sensitivity of three loci on the tongue and soft palate to four basic tastes in smokers and non-smokers. Acta Oto-Laryngologica. 2002 Jan 1;122(4):74-82.
[32] Hilgers KK, Kinane DF. Smoking, periodontal disease and the role of the dental profession. International journal of dental hygiene. 2004 May;2(2):56-63.
[33] Lie MA, Van der Weijden GA, Timmerman MF, Loos BG, Van Steenbergen TJ, Van der Velden U. Oral microbiota in smokers and non‐smokers in natural and experimentally‐induced gingivitis. Journal of clinical periodontology. 1998 Aug;25(8):677-86.
[34] Stoltenberg JL, Osborn JB, Pihlstrom BL, Herzberg MC, Aeppli DM, Wolff LF, Fischer GE. Association between cigarette smoking, bacterial pathogens, and periodontal status. Journal of periodontology. 1993 Dec;64(12):1225-30.
[35] Kamma JJ, Nakou M, Baehni PC. Clinical and microbiological characteristics of smokers with early onset periodontitis. Journal of periodontal research. 1999 Jan;34(1):25-33.
[36] Zambon JJ. Periodontal diseases: microbial factors. Annals of periodontology. 1996 Nov;1(1):879-925.
[37] Söder B, Jin LJ, Wickholm S. Granulocyte elastase, matrix metalloproteinase‐8 and prostaglandin E2 in gingival crevicular fluid in matched clinical sites in smokers and non‐smokers with persistent periodontitis. Journal of Clinical Periodontology. 2002 May;29(5):384-91.
[38] Barbour SE, Nakashima K, Zhang JB, Tangada S, Hahn CL, Schenkein HA, Tew JG. Tobacco and smoking: environmental factors that modify the host response (immune system) and have an impact on periodontal health. Critical Reviews in Oral Biology & Medicine. 1997 Oct;8(4):437-60.
[39] Hind CR, Joyce H, Tennent GA, Pepys MB, Pride NB. Plasma leucocyte elastase concentrations in smokers. Journal of clinical pathology. 1991 Mar 1;44(3):232-5.
[40] Lang NP, Lindhe J, editors. Clinical periodontology and implant dentistry, 2 Volume Set. John Wiley & Sons; 2015 Mar 25.
[41] Alavi AL, Palmer RM, Odell EW, Coward PY, Wilson RF. Elastase in gingival crevicular fluid from smokers and non‐smokers with chronic inflammatory periodontal disease. Oral Diseases. 1995 Sep;1(3):110-4.
[42] Pauletto NC, Liede K, Nieminen A, Larjava H, Uitto VJ. Effect of cigarette smoking on oral elastase activity in adult periodontitis patients. Journal of Periodontology. 2000 Jan 1;71(1):58-62.
[43] Offenbacher S. Periodontal diseases: pathogenesis. Annals of periodontology. 1996 Nov;1(1):821-78.
[44] Laxman VK, Annaji S. Tobacco use and its effects on the periodontium and periodontal therapy. J Contemp Dent Pract. 2008 Nov 1;9(7):97-107.
[45] Fiore MC. A clinical practice guideline for treating tobacco use and dependence: a US Public Health Service report. JAMA: Journal of the American Medical Association. 2000 Jun.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.