SELENIUM NANOPARTICLES AND ITS APPLICATION
DOI:
https://doi.org/10.61841/xfp6dm74Keywords:
Antimicrobial activity, Anticancer, Nanoparticle, Selenium, AntioxidantAbstract
Selenium is an important trace element within the diet, required for protection of health and growth; however, its toxicity could cause extreme damage depending on dose and chemical form. Selenium nanoparticles (SeNPs) represent a prospect for nutritional supplementation due to their decreased toxicity and capacity to gradually release selenium after ingestion. Selenium nanoparticles (SeNPs), as a special shape of selenium (Se) supplement, have attracted worldwide attention because of their favorable properties and unique bioactivities. A green and economic way to prepare stable SeNPs has been introduced. Selenium nanoparticles serve to reduce the toxicity and enhance bioactivity. The aim of the present study is to analyse the properties and applications of selenium nanoparticles. Here we have discussed the significance of the selenium nanoparticles and their pharmacological activity. The role of selenium nanoparticles in pharmacological protection against various conditions is presented.
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1. Skalickova S, Milosavljevic V, Cihalova K, Horky P, Richtera L, Adam V. Selenium nanoparticles as a nutritional supplement [Internet]. Vol. 33, Nutrition. 2017. p. 83–90. Available from: http://dx.doi.org/10.1016/j.nut.2016.05.001
2. Hassanin KMA, Abd El-Kawi SH, Hashem KS. The prospective protective effect of selenium nanoparticles against chromium-induced oxidative and cellular damage in rat thyroid. Int J Nanomedicine.2013 May 1;8:1713–20.
3. Sarkar B, Bhattacharjee S, Daware A, Tribedi P, Krishnani KK, Minhas PS. Selenium Nanoparticles for Stress-Resilient Fish and Livestock. Nanoscale Res Lett. 2015 Dec;10(1):371.
4. Samuel AR, Devi MG. Geographical distribution and occurrence of Endemic Goitre. Research Journal of Pharmacy and Technology. 2015;8(8):973–8.
5. Baheerati MM, Devi RG. Obesity in relation to Infertility. Research Journal of Pharmacy and Technology.2018;11(7):3183–5.
6. Fathima F. Preetha. Evaluation of Thyroid Function Test in Obese Patients. Asian J Pharm Clin Res.2016;9(3):353–5.
7. Rj I, R GD. Role of environmental factors on sleep patterns of different age groups [Internet]. Vol. 9, Asian Journal of Pharmaceutical and Clinical Research. 2016. p. 124. Available from:http://dx.doi.org/10.22159/ajpcr.2016.v9i6.13832
8. Harsha L, Priya J, Shah KK. Systemic approach to management of neonatal jaundice and prevention of kernicterus. Research Journal of [Internet]. 2015; Available from: http://www.indianjournals.com/ijor.aspx?target=ijor:rjpt&volume=8&issue=8&article=028
9. Abigail, Priya J., Devi G. Evaluation of Muscular Endurance among Dentists. Indian Journal of Public Health Research & Development. 2019;10(10):258–61.
10. David, Priya AJ, Devi G. Physical Fitness among the Dental Physician, Dental Undergraduates, and Postgraduate Students. Indian Journal of Public Health Research & Development. 2019;10(10):223-6.
11. Dave PH, Others. Pathogenesis and Novel Drug for Treatment of Asthma—A Review. Research Journal of Pharmacy and Technology. 2016;9(9):1519–23.
12. Choudhari S, Jyotipriya MA. Non-alcoholic fatty liver disease [Internet]. Vol. 9, Research Journal of Pharmacy and Technology. 2016. p. 1782. Available from: http://dx.doi.org/10.5958/0974-360x.2016.00360.7
13. Swathy S, Sethu VG. Acupuncture and lower back pain. Research Journal of Pharmacy and Technology. 2015;8(8):991–3.
14. Shruthi M., Preetha S. Effect of Simple Tongue Exercises in Habitual Snorers. Research Journal of Pharmacy and Technology. 2018;11(8):3614–6.
15. Timothy CN, Devi RG, Priya AJ. Evaluation of Peak Expiratory Flow Rate (PEFR) in Pet Owners. Indian Journal of Public Health Research & Development. 2019;10(8):803-6.
16. Renuka S, Sethu G. Regeneration after Myocardial Infarction. Research Journal of Pharmacy and Technology. 2015;8(6):738–41.
17. Gayatri DR, Sethu G. EVALUATION OF ADENOIDS BY ORONASAL AND NASAL SPIROMETRY. Evaluation [Internet]. 2018;11(10). Available from: https://innovareacademics.org/journals/index.php/ajpcr/article/download/27365/15808
18. Iyer PK, Devi RG, Priya AJ. A Survey Study on Causes, Treatment, and Prevention of Onychocryptosis. Indian Journal of Public Health Research & Development. 2019;10(8):807–11.
19. Chhabria S., Desai K. Selenium nanoparticles and their applications. Encyclopedia of Nanoscience and [Internet]. 2016; Available from:
20. Sakr TM, Korany M, Katti KV. Selenium nanomaterials in biomedicine—An overview of new opportunities in nanomedicine of selenium. J Drug Deliv Sci Technol [Internet]. 2018; Available from: https://www.sciencedirect.com/science/article/pii/S1773224718301679
21. McKenzie RC, Arthur JR, Beckett GJ. Selenium and the regulation of cell signaling, growth, and survival: molecular and mechanistic aspects. Antioxid Redox Signal. 2002 Apr;4(2):339–51.
22. Yu B, Zhang Y, Zheng W, Fan C, Chen T. Positive surface charge enhances selective cellular uptake and anticancer efficacy of selenium nanoparticles. Inorg Chem. 2012 Aug 20;51(16):8956–63.
23. Zhai X, Zhang C, Zhao G, Stoll S, Ren F, Leng X. The antioxidant capacities of the selenium nanoparticles stabilized by chitosan. J Nanobiotechnology. 2017 Jan 5;15(1):4.
24. Fernández-Martínez A, Charlet L. Selenium environmental cycling and bioavailability: a structural chemist point of view. Rev Environ Sci Technol. 2009 Mar 1;8(1):81–110.
25. Zhang J. Evaluation of nanotoxicity of foods and drugs: Biological properties of red elemental selenium at nanosize (nano-Se) in vitro and in vivo. Nanotoxicity: From In Vivo and In Vitro Models to Health Risks; Saura, CS, Daniel, AC, Eds. 2009;97–113.
26. Husen A, Siddiqi KS. Plants and microbes-assisted selenium nanoparticles: characterization and application. J Nanobiotechnology. 2014 Aug 16;12:28.
27. Tran PA, Webster TJ. Selenium nanoparticles inhibit Staphylococcus aureus growth. Int J Nanomedicine. 2011 Jul 29;6:1553–8.
28. Liu W, Li X, Wong Y-S, Zheng W, Zhang Y, Cao W, et al. Selenium nanoparticles as a carrier of 5-fluorouracil to achieve anticancer synergism. ACS Nano. 2012 Aug 28;6(8):6578-91.
29. Wadhwani SA, Shedbalkar UU, Singh R, Chopade BA. Biogenic selenium nanoparticles: current status and future prospects. Appl Microbiol Biotechnol. 2016 Mar;100(6):2555–66.
30. Bi X, Kong L, Yuan Q, Zhu H, Gao X. Abstract 2910: Selenium nanoparticles suppress prostate LNCaP cancer cell growth through induced endogenous apoptosis [Internet]. Cancer Chemistry. 2012. Available from: http://dx.doi.org/10.1158/1538-7445.am2012-2910
31. Guo M, Li Y, Lin Z, Zhao M, Xiao M, Wang C, et al. Surface decoration of selenium nanoparticles with curcumin-induced HepG2 cell apoptosis through ROS-mediated p53 and AKT signaling pathways [Internet]. Vol. 7, RSC Advances. 2017. p. 52456–64. Available from:http://dx.doi.org/10.1039/c7ra08796a
32. Xia Y, Lin Z, Li Y, Zhao M, Wang C, Guo M. Targeted delivery of siRNA using RGDfC-conjugated functionalized selenium nanoparticles for anticancer therapy. Proc Inst Mech Eng Part L J Mat Des Appl [Internet]. 2017; Available from: https://pubs.rsc.org/ko/content/articlehtml/2017/tb/c7tb01315a
33. Farhat Yaasmeen Sadique Basha, Rajeshkumar S., Lakshmi T., Anti-inflammatory activity of Myristica fragrans extract. Int. J. Res. Pharm. Sci., 2019 ;10(4), 3118-3120 DOI: https://doi.org/10.26452/ijrps.v10i4.1607
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