AN OVERVIEW OF NASAL LUBRICANT FORMULATION
DOI:
https://doi.org/10.61841/m71gk483Keywords:
nasal lubricant, nasal moisturizer, nasal irrigationAbstract
The aim of this overview is to provide information on current research and literatures relating to nasal lubricants. Drawing upon the MEDLINE database from 1945 to 2011, in addition to other relevant sources, this overview specifically discusses and evaluates various formulations and usages of nasal lubricant, their mechanism of action, associated with nasal irrigation, as well as additives used in nasal lubricant products. It is found that although nasal irrigation or nasal lubricant basically serves the same purpose and represents a costeffective method of alleviating symptoms of nasal diseases, the effects of additives used in their formulations have yet to be carefully studied.
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References
[1] Bachman, G., Hommel, G. & Michel, O. (2000) Effect of irrigation of the nose with isotonic salt solution on
adult patients with chronic paranasal sinus diseases. Eur.Arc. Otorhinolaryngol. 257, p. 537-541.
[2] Boek, W., Keles N., Graamans K. & Huizing E.H. (1999) Physiologic and Hypertonic Saline Solutions Impair
Ciliary Activity in Vitro. Laryngoscope, 109 (3). March, p.396-399.
[3] Davidson T.M. & Murphy C. (1997) Rapid clinical evaluation of anosmia: the alcohol sniff test. Arch.
Otolaryngol. Head Neck Surg. 123, p. 591-594.
[4] Evans, K. L. (1994) Diagnosis and management of sinusitis. British Medical Journal. 309, p. 1415-1422.
[5] Goh, Y.H. & Goode R. L. (2000) Current status of topical nasal antimicrobial agents. The Laryngoscope. 110
June, p. 875-880.
[6] Hellgren, J., Ericksson, C., Karlson, G. & Hagberg, S. (2001) Nasal symptoms among workers exposed to soft
paper dust. Int. Arc. Occup. Environt. Health. 74, p. 129-132.
[7] Homer, J.J., Endland, R.J., Wilde, A.D., Hardwood, G.R.J., & Stafford, N.D. (1999) The effect of pH douching
solutions on mucociliary clearance. Clinical Otolaryngology and Allied Sciences. 24(4) August, p. 312-315.
[8] Heatly D.G., McConnell K.E., Kille T.L. & Leverson G.E. (2001) nasal irrigation for
[9] the alleviation of sinonasal symptoms. Otolaryngol. Head Neck Surg. 125, p. 44-48.
[10] Jabarullah, N.H. (2019) Production of olefins from syngas over Al2O3 supported Ni and Cu nano-catalysts,
Petroleum Science and Technology, 37 (4), 382 – 385.
[11] Luk C.K. and Dulfano M.J. (1983) Effect of pH, viscosity and ionic-strength changes on ciliary beating
frequency of human bronchial explants. Clinical Science. 64, p. 449-451..
[12] Ludman, H. (1981) ABC of Otolaryngology. BMJ Publishing Group, London, p. 40- 46
[13] Lund W., (Ed). (1994) The Pharmaceutical Codex, 12th edn, pp. 67-68. The Pharmaceutical Press, London.
[14] Meoli AL, Rosen CL, Kristo D. (2003) Nonprescription treatments of snoring or obstructive sleep apnea: an
evaluation of products with limited scientific evidence. Sleep.
[15] Miller, O.K. (1990) Otic Products, In Handbook of Nonprescription Drugs. The National Professional Society of
Pharmacists, Washington, p. 89-103.
[16] Mygind N. (1979) Nasal Allergy. Oxford, London: Blackwell Scientific Publications.
[17] Naspitz C.K. and Tinkelman D. G. (1990) Childhood Rhinitis and Sinusitis. Phatophysiology and Treatment.
New York: Marcel Dekker, Inc..
[18] Reynolds, J.E.F. (1992) Martindale, The extra Pharmacopeia. The Council of the Royal Pharmaceutical Society
of Great Britain.
[19] Robinson M., Hemming A.L., Regnis J.A., Wong A.G., Bailey D.L., Bautovich G.J., King M. & Peter T.P.B.
(1997) Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis.
Thorax. 52, p. 900-903.
[20] Robinson M., Regnis J.A., Bailey D.L., King M., Bautovich G.J., & Bye P.T.P. (1996) Effect of Hypertonic
saline, Amiloride, and cough on mucociliary clearance in patients with cystic fibrosis. Am. J. Respir. Crit. Care
Med. 153, p. 1503-1509.
[21] Shoseyov, D., Bibi, H., Shai, P., Shoseyov, N., Shasberg, G. & Hurvitz, H. (1998) Treatment with hypertonic
saline versus normal saline nasal wash of pediatric chronic sinusitis. The Journal of Allergy and Clinical
Immunology. 101(5), May, p. 602-605.
[22] Shaikh W.A. (1995) Ephedrine-saline nasal wash in allergic rhinitis. J. Allergy Clin. Immunol. 96, p. 597-600.
[23] Spraggs P.D., Macnamara M. & Joseph T. (1995) A propective randomized study to Assess the efficacy of postoperative nasal medication after endonasal surgery. The Journey of Laryngology and Otology. July 109, p. 618-621.
[24] The United States Pharmacopeial convention. (1995) The United States Pharmacopeia. The National Formulary, The United States Pharmacopeial Convention, Inc., Reckville.
[25] Talbot, A.R., Herr, T.M. & Parsons, D.S. (1997) Mucociliary clearance and buffered hypertonic saline solution.The Laringoscope. 107, 500-503.
[26] Tomooka, L.T., Murphy C. & Davidson T.M. (2000) Clinical study and literature Review of nasal irrigation. Laryngoscope. 110 July, p. 1189-1192.
[27] Thomson C. & Negus V.E. (1948) Disease of the nose and throat. London: Cassel and Company, LTD.
[28] Wallace D.J. & Bromet E.J. (Eds). (2005). The new Sjogren's syndrome handbook (3rd ed.). Sjogren's Syndrome Foundation. Oxford University Press.
[29] Wills P.J., Hall R.L., Chan W. & Cole P.J. (1997) Sodium chloride increases the ciliary transportability of cystic fibrosis and bronchiectasis sputum on the mucus-depleted bovine trachea. J. Clin. Invest. 99, No. 1 January, p. 9-13.
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