Clinical Case of Primary Sclerosing Cholangitis on the Crohn's Disease of the Upper Gastrointestinal Parts Background

Authors

  • Ekaterina V. Pazenko Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author
  • Karina L. Raikhelson Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author
  • Elina A. Kondrashina Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author
  • Lyudmila K. Palgova Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author
  • Vadim E. Karev Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author
  • Natalya V. Marchenko Federal State Budgetary Educational Institution of Higher Education "Saint-Petersburg State University", Junior Researcher, Saint Petersburg, Russian Federation Author

DOI:

https://doi.org/10.61841/kydn8s09

Keywords:

Crohn’s disease, primary sclerosing cholangitis, gastrointestinal tract, rare pathology combination, biopsy

Abstract

Inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC) are two separate diseases, with still unclear etiologies that continue to be investigated. Clinic manifestation of IBD-PSC is different from separate clinics of these diseases. A great portion of different scientific surveys witness of connection between IBD and PSC. Still, there is no enough data to perform a large randomized trial for imaging a clear picture of the IBD-PSC connection condition. Most prevalent is a combination between primary sclerosing cholangitis and ulcerative colitis. In our clinical case, we headed with a combination of primary sclerosing cholangitis and stomach form of Crohn’s disease (CD). The following clinical survey showed a rare case of primary sclerosing cholangitis with stomach's Crohn's disease combination, which was complicated by difficulties in diagnostic and correct treatment tactic selection. We tracked our patient from the beginning of first gastrointestinal symptoms in 2006 when gastric ulcer was revealed and 2014 when chronic gastric ulcer was diagnosed towards 2017 when our department visiting a patient was diagnosed rare gastric Crohn’s disease form and primary sclerosing cholangitis with ulterior colitis development in 2019. Further clinical examinations of similar clinical cases will confirm or deny out the assumption of a connection between gastric Crohn's disease and primary sclerosing cholangitis.

 

 

 

Downloads

Download data is not yet available.

References

1. Delhet P. Rétrécissement du cholédoque: cholécystoduodénostomie. Bull Mem Soc Nat Chir. 1924; 50: 1144–1146.

2. Chapman R et al. Diagnosis and management of primary sclerosing cholangitis. Hepatology. 2010; 51 (2): 660–678.

3. Ivashkin VT, Sheptulina AF, Raikhelson KL. Digestive autoimmune diseases. Ann Rus Aca Med Sci. 2015; 70 (2): 139–152.

4. Smith MP, Loe RH. Sclerosing cholangitis; review of recent case reports and associated diseases and four new cases. Am. J. Surg. 1965; 110: 239–246.

5. de Vries AB et al. Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis. J Gastroenterol. 2015; 21: 1956–1971.

6. Rasmussen HH, et al.: Hepatobiliary dysfunction and primary sclerosing cholangitis in patients with Crohn's disease. Scand J Gastroenterol. 1997; 32: 604–610.

7. Ang TL, et al. Clinical profile of primary sclerosing cholangitis in Singapore. J Gastroenterol Hepatol. 2002; 17: 908–913.

8. Escorsell A, et al. Epidemiology of primary sclerosing cholangitis in Spain. J Hepatol. 1994; 21: 787–791.

9. Eaton JE, et al. Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management. Gastroenterology. 2013; 145: 521–536.

10. Loftus EV Jr, et al. PSC — IBD: a unique form of inflammatory bowel disease associated with primary sclerosing cholangitis. Gut. 2005; 54: 91–96.

11. de Vries AB, et al. Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis, World J Gastroenterol, 2015; 21(6): 1956–1971.

12. Sokol H, et al. Disease activity and cancer risk in inflammatory bowel disease associated with primary sclerosing cholangitis, World J Gastroenterol, 2008; 14: 3497–3503.

13. Halliday JS, et al. A unique clinical phenotype of primary sclerosing cholangitis associated with Crohn’s disease. J Crohn’s Colitis, 2012; 6: 174–181.

14. Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL). Clin Gui J of Hepatology. 2017; 66j: 1265–1281.

15. Crohn B, Ginsburg l, Oppenheimer G. Regional ileitis: A pathological and clinical entity. JAMA. 1932; 99: 1323–1329.

16. Ross J. Cicatrizing enteritis, colitis and gastritis: a case report. Gastroenterology. 1949; 13: 344–50.

17. Gomollоn F, et al. 3rd European Evidence — based Consensus on the Diagnosis and Management of Crohn’s Disease 2016: Part 1: Diagnosis and Medical Management. Journal of Crohn's and Colitis. 2016; 11 (1): 3–25.

18. Ingle SB, et al. Isolated gastric Crohn’s disease. World J Clin Cases. 2013; 1(2): 71–73.

19. Feuerstein JD, Cheifetz AS. Crohn Disease: Epidemiology, Diagnosis, and Management. Mayo Clinic Proceedings. 2017; 92 (7): 1088–1103.

20. Reynolds HL, Stellato TA. Crohn's disease of the foregut. Surg Clin North Am. 2001; 81: 117–135.

21. Maaser C, et al. ECCO — ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications. Journal of Crohn's and Colitis. 2018; 13 (2): 144–164K.

22. Ivashkin VT, et al. Diagnostics and treatment of diverticular disease of the colon: guidelines of the Russian gastroenterological Association and Association of Coloproctology. 2016; Available at https://www.gastro-j.ru/jour/article/view/23/11

23. Van Hogezand RA, et al. Proximal Crohn's disease: review of the clinicopathologic features and therapy. Inflamm Bowel Dis. 2001; 7: 328–337.

24. Magro F, et al: European Society of Pathology; European Crohn's and Colitis Organisation. European consensus on the histopathology of inflammatory bowel disease. J. Crohns Colitis. 2013; 7(10): 827–851.

25. Shchukina OB, et al. Diagnostic and prognostic value of some morphological signs of Crohn's disease. Doctor.ru. 2013; 9 (87): 82–88.

26. Lee WI, et al. The significance of ANCA positivity in patients with inflammatory bowel disease. Pathology. 2019; 51(6): 634–639.

27. Pokorny CS, et al.: Anti — neutrophil cytoplasmic antibody: A prognostic indicator in primary sclerosing cholangitis. Gastroenterology and Hepatology. 1994; 40–44.

28. Keith D et al.: ACG Clinical Guideline: Primary Sclerosing Cholangitis, Gastroenterology, 2015; 110(5): 646–659.

29. Raikhel'son KL, et al. Morphological differential diagnosis of autoimmune liver diseases in clinical practice. Profilactical & Clinical Medicine. 2013; 2 (47): 43–49.

30. Chapman MH, et al. British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis. Gut. 2019; 68: 1356–1378.

31. Torres J, et al.: ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment. Journal of Crohn's and Colitis. 2020; 14 (1): 4–22.

32. Iny O et al. Crohn's Disease Behavior and Location is Altered when Associated with Primary Sclerosing Cholangitis. Isr Med Assoc J. 2018; 20(1): 25–29.

33. Lindor KD, et al. High - dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis. Hepatol. 2009; 50(3): 808–814.

34. Pardi, DS, et al. Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis. Gastroenterol. 2003; 124 (4): 889–893.

35. Solovyeva E. Nonlinear models of digital filters and their application fields // XV International Symposium “Problems of Redundancy in Information and Control Systems” (REDUNDANCY). – St. Petersburg: Saint-Petersburg State University of Aerospace Instrumentation. Russia, St. Petersburg, September 26−29, 2016, P. 150–154. DOI: 10.1109/RED.2016.7779351

36. Solovyeva E. Cellular neural network as a non-linear filter of impulse noise // Proceedings of the 20th Conference of Open Innovations Association FRUCT (FRUCT20). – St. Petersburg: Saint-Petersburg Electrotechnical University “LETI” and Technopark of ITMO University. Russia, St. Petersburg, April 3−7, 2017, P. 420–426. DOI: 10.23919/FRUCT.2017.8071343

Downloads

Published

31.10.2020

Issue

Vol. 24 No. 8 (2020): 24 (8) 2020

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

  1. Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
  2. Adapt — remix, transform, and build upon the material for any purpose, even commercially.
  3. The licensor cannot revoke these freedoms as long as you follow the license terms.

Under the following terms:

  1. Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  2. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Notices:

You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .

No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.

How to Cite

Pazenko, E. V., Raikhelson, K. L., Kondrashina, E. A., Palgova, L. K., Karev, V. E., & Marchenko, N. V. (2020). Clinical Case of Primary Sclerosing Cholangitis on the Crohn’s Disease of the Upper Gastrointestinal Parts Background. International Journal of Psychosocial Rehabilitation, 24(8), 11428-11442. https://doi.org/10.61841/kydn8s09