Initial troponin as a Predictor of High Thrombus Burden in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Background: Intracoronary thrombus management is still challenging, despite recent major pharmacological and invasive improvements,such as glycoprotein IIb/IIIa antagonists or thrombectomy, respectively, in percutaneous coronary intervention (PCI). Intracoronary thrombus burden is still a risk factor for long-term adverse cardiovascular events, stent thrombosis, no reflow, and distal embolization. Establishing the predictors of intracoronary thrombus and associated clinical and angiographic conditions, therefore, may provide improvements in its management. To address this issue, we aimed to investigate Initial troponin as a Predictor of High Thrombus Burden in Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary InterventionMethods: The current study is a cross-sectional study involving 180 patients with acute myocardial infarction undergoing primary percutaneous coronary intervention, admitted to the Coronary Care Unit in Zagazig University Hospitals in the period between January 2019 and January 2020. They were classified into two groups: Group 1 (Low thrombus burden of culprit vessel). Group 2 (High thrombus burden culprit vessel).Results:Regarding univariate logistic regression, predictors of high thrombus burden that showed high statistically significance include initial troponin. Roc carve showed cut-off value (1110.5) pg./mL for initial troponin to predict high thrombus burden with sensitivity (89.60%) and specificity (79.40%) and AUC (0.853). Conclusion: Initial troponin, was determined as predictor of high thrombus burden in acute STEMI patients undergoing primary PCI.