Effect of benzene fuel on IgE, SIgA, Alpha amylase for workers in filling stations in Basrah, Iraq

Study aimed to determined the effect benzene fuel on immunity of workers in filling stations by estimating the level of immunological parameters(IgE, SIgA, Alpha amylase). Seventy samples were collected from the gas station workers and twenty saliva sample were collected from neither works nor lives near gas fumes. The collection period of the saliva began from September and ended in November 2019. Samples were collected at 3 ml in 50 ml tubes. Results showed that the level of T. IgE >3 was the highest amongst the gas station filling workers at rate 31.42 % compared with of those who don’t work at gas stations with a significant difference at probability level p ≤ 0.05,but the result showed that of T. IgE <3 was the highest at rate 68.58 % compared with workers .also this study showed decreased total IgE in 3rd age group at rate 43% ,while increase total IgE in 1st age group with significant different compared with other ages groups . as well as study showed that level of T. IgA increase in 1st group at rate 28.58% compared with 2nd group with a significant difference at probability level P ≤ 0.05.futhermore ,the results showed that T. IgA increase in 2 nd age group (40-31) year at rate 43% ,and decreased total IgA in 4th age group (41-50)year at rate 80% with a significant difference at probability level P ≤ 0.05 compared with other ages groups .as well as the study showed the level of α Amylase level in the saliva of gas station employees it was observed that increase at rate 81.43% comparison of the control samples with a significant difference at probability level P ≤ 0.05. also current study showed α Amylase> 1000 in the saliva of gas station employees in the age group 18-30 years at rate 86%, while the α Amylase >1000 was higher in the age group (31-40) at rate 28%, with a significant difference at probability level P ≤ 0.05. study showed that an increase in a α Amylase> 1000 at rate (81.4%) in comparison of the other immunological norms with a significant difference P≤ 0.05 . observed that an increase in the level of IgE , α Amylase accompanies the decrease of T. IgA We in comparison of controlled samples.we Conclusion benzene fuel affects the immune system of workers at filling stations. for that we think this is the reason for the increased severity of allergies, as well as the inability to fight bacterial infection.