A Histopathological Study of Endometrium in Abnormal Uterine Bleeding: A Retrospective Study

Background: Abnormal uterine bleeding (AUB) is a common gynecological complaint associated with considerable morbidity and significantly affects the patient’s family, personal and social life. The study aimed was to analyze the histomorphological patterns of endometrium in patients presenting with AUB and also to determine the incidence of AUB in various age groups. Methods: This type of research is a descriptive study with a cross-sectional approach. Data was taken from medical records of the patients with a diagnosis of Abnormal Uterine Bleeding by dilatation and curettage and then by a histopathological laboratory examination at the K.R.M.T Wongsonegoro Hospital Semarang, Indonesia. Results: A total of 87 cases were analyzed. The patient’s age ranged from 19-68 years old. Body Mass Index (BMI) divided three groups: Normal weight 27%, overweight 35.6% and obese 36.8%. Endometrial hyperplasia was the most common histopathological finding and was seen in 29.9% of patients, followed by irregular shedding 24.13%, disorder proliferative pattern 17.24%, proliferative with glandular and stromal breakdown 9.19%, Progestin effect 6.89%. Statistical test results with chi-square relationship between BMI with histopathological features is p = 0.290. Conclusion: Statistical test results showed no relationship between age and BMI with histopathological results. We found that hyperplasia endometrium is the commonest cause of abnormal uterine bleeding.