Evaluation of Breast cancer Treatment in AlHussein Hospital in Karbala city (A Descriptive Study)
DOI:
https://doi.org/10.61841/jt3h5d22Keywords:
Al-Hussein Hospital, Breast cancer Treatment, Karbala cityAbstract
Background: breast conserving surgery provide good choice for treatment of stage 1 and II breast cancer and has equivalent out come in term of survival and prognosis.
Aims of the Study: To evaluate breast cancer treatment according to multiple variables and patient's wish in Alhussain hospital in Karbala city.
Patient and methods: - The present study is considered as a descriptive study, which has been conducted at AI-Imam AI-Hussein medical city in Karbala governorate during the period from 1st September 2017 to the 30 of December 2018. Fifty-two patients included in the study were admitted to the general surgical ward. The entire patients were first visiting the breast clinic or general surgical out-patient clinic or private clinic, every case is assessed by triple assessment (history and clinical examination, imaging study, histological diagnosis). Each case was presented and discussed in MDT (multidisciplinary team), after that we do the operation (wide local excision) and the specimen without formalin send for the lab. unit in our hospital for diagnosis and assessment of the margins, the result usually come after 20-30 minutes.
As the result come back, if the margins were free then we start with axillary dissection or we do re-excision if the margins were positive and then the wound closed with closed system drain after secure hemostasis, and the axillary dissection is standard to the level II L.N dissection.
Results: Fifty-two patients with breast cancer included in our study, twenty three patients (44%) were treated by mastectomy and twenty nine patients (56%) were treated by breast conserving surgery.
The most common type was invasive ductal carcinoma, which can be treated by either modality (breast-conserving surgery or mastectomy).
A sentinel lymph node biopsy (S.L.N.B) is important to avoid negative axillary dissection.
In conclusions, screening program for breast cancer to detect early disease is very important subject before proceeding to axillary dissection S.L.N.B is very important and useful. The choice of Mastectomy was lower than that of Breast Conserving Surgery in our study for early treatment with breast cancer.
Downloads
References
1. Susan C.Lester, MD, PhD: Robbins and8 Cotran: ELSEIER SOUNDER; Pathologic Bases of Disease 7th ed.: the
Breast p1123:
2. Daron JM. et al: long term survival after breast cancer.Br J Surgery72:445,1985 .
3. Armando E.Giuliano,MD.Lawrence W.Way;CurrentSurgical Diagnosis and Treatment,11th Ed ,Doherty;Mc Graw
Hill, Breast,P319-329.
4. Bennett S, Kaelin CM: Benign breast disease. In Branch WT (ed): office Practice of Medicine, 3th ed. Philadelphia,WB Saunders,2003, pp545
5. Wilkinson EJ, Masood S: Cytologic needle samplings of the breast: Techniques and end results, in bland KI, EM
III (EDS): The Breast: Comprehensive Management Diseases. Philadelphia: WB Saunders. 1998, p 705
6. Barton MB, Elmore JG, Fletcher, and SW: Breast symptoms among women enrolled in a health maintenance
organization: frequency, evaluation and outcome. Ann Intern Med 130:651, 1999
7. Ali, A. A., & Al Helli, A. A. (2007). Women Breast Diseases in Karbala Epidemiology and Workup. Karbala Journal
of Medicine, 1(1), 116-123.
8. Senkus E, Kyriakides S, Ohno S, et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis,
treatment and follow-up. Ann Oncol 2015; 26(Suppl. 5):v8–v30.
9. Cardoso F, Costa A, Norton L, et al. ESO-ESMO 2nd international consensus guidelines for advanced breast cancer
(ABC2). Ann Oncol 2014; 25: 1871–1888.
10. Torre, L.A.; Bray, F.; Siegel, R.L.; Ferlay, J.; Lortet-Tieulent, J.; Jemal, A. Global cancer statistics, 2012. CA Cancer
J. Clin. 2015, 65, 87-108. [CrossRef] [PubMed
11. American Cancer Society. Breast Cancer Facts & Figures 2017-2018. Available at
12. Noone AM, Howlader N, Krapcho M, et al. (editors). SEER Cancer Statistics Review, 1975-2015. Table 1.12. Median
age of cancer patients at diagnosis, 2011-2015. National Cancer Institute. Bethesda, MD. Accessed on April 19, 2018.
http://seer.cancer.gov/csr/1975_2015/, 2018.
13. Michailidou K, Lindström S, Dennis J, Beesley J, Hui S, Kar S, Lemaçon A, Soucy P, Glubb D, Rostamianfar A,
Bolla MK. Association analysis identifies 65 new breast cancer risk loci. Nature. 2017 Nov;551(7678):92.
14. Von Karsa L, Qiao Y, Ramadas K, Keita N, Arrossi S, et al. (2014) Prevention/Screening Implementation, in Stewart
BW and Wild CP (eds): World Cancer Report 2014. World Health Organization International Agency for Research
on Cancer, Lyon, France.
15. Liu N, Johnson KJ, Ma CX. Male breast cancer: an updated surveillance, epidemiology, and end results data analysis.
Clinical breast cancer. 2018 Oct 1;18(5):e997-1002.
16. Molecular Pathology (Second Edition), male breast cancer 2018. 345.
17. Tung N, Lin NU, Kidd J, Allen BA, Singh N, Wenstrup RJ, Hartman AR, Winer EP, Garber JE. Frequency of germline
mutations in 25 cancer susceptibility genes in a sequential series of patients with breast cancer. Journal of Clinical
Oncology. 2016 May 1;34(13):1460.
18. Schaapveld M, Aleman BM, van Eggermond AM, Janus CP, Krol AD, van der Maazen RW, Roesink J, Raemaekers
JM, de Boer JP, Zijlstra JM, van Imhoff GW. Second cancer risk up to 40 years after treatment for Hodgkin’s
lymphoma. New England Journal of Medicine. 2015 Dec 24;373(26):2499-511.
19. National Institutes of Health Consensus Development Panel Consensus Statement. Treatment of early-stage breast
cancer. J Natl Cancer Inst Monogr. 1992; 11:11.
20. Joudeh AA, Shareef SQ, Al-Abbadi MA. Fine-needle aspiration followed by core-needle biopsy in the same setting:
modifying our approach. Acta cytologica. 2016;60(1):1-3. doi:10.1159/000444386. PMID 26963594.
21. Park HL, Hong J. Vacuum-assisted breast biopsy for breast cancer. Gland surgery. 2014 May;3(2):120.
doi:10.3978/j.issn.2227-684X.2014.02.03. ISSN 2227-684X. PMC 4115763. PMID 25083505.
22. Halsted WS. The results of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital
from June 1889 to January 1894. Johns Hopkins Hospital Reports. 1894–1895; 4:297–350.
23. Onega T., Goldman L.E., Walker R.L., Miglioretti D.L., Buist D.S., Taplin S., Geller B.M., Hill D.A., Smith-Bindman
R. Facility mammography volume in relation to breast cancer screening outcomes. J. Med. Screen. 2016;23:31. doi:
10.1177/0969141315595254. [PubMed] [CrossRef]
24. Ozmen N., Dapp R., Zapf M., Gemmeke H., van Ruiter N.V., Dongen K.W. Comparing different ultrasound imaging
methods for breast cancer detection. IEEE Tran. Ultrason. Ferroelectr. Freq. Control. 2015;62:637–646. doi:
10.1109/TUFFC.2014.006707. [PubMed] [CrossRef]
25. Lames H. Almanseekanaa, Raed H. Ogaili & SSMB. Interpretations of hematological findings among Iraqi children
with celiac disease in Kerbala city. Int J Res Pharm Sci [Internet]. 2019;10(1):641–4. Available from:
https://www.pharmascope.org/index.php/ijrps/article/view/117
26. Al-Tai AHAS, Ogaili RH. Assessment of hemorrhoids surgical intervention among 180 patients in Karbala city.
Biochem Cell Arch. 2019;19(2).
27. Abdulsattar, M. S., Ogaili, R. H., Almanseekanaa, L. H., & AlaaJasim Mohamed Ali. Epidemiological analysis of 57
maxillofacial trauma cases. Biochemical and Cellular Archives,2019. 19(2), 3159–3164.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 AUTHOR

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.