Demographic and Clinicopathological characteristics of breast cancer patients, Baghdad, Iraq
DOI:
https://doi.org/10.61841/gqwcst71Keywords:
demographic, clinicopathologicalAbstract
Background: Breast cancer is the most common cancer affecting women all over the world. Breast cancer is the most frequent cancer among women in Iraq. Objectives: to highlight the main demographic characteristics and clinicopathological characteristics of female patients registered with breast cancer in Iraq. Method: A retrospective study done on 264 diagnosed breast cancer cases during period of 2017 and 2018 among women records of attendees to women health center in AL-ELWYIA maternity teaching hospital. Results: the mean age at presentation was 50.8 years ,patients under age of 40 years constitute 18.9% and those between 50-59 years constitute 29.5% ,about 69.7% of the patients had more than two children , 72% of patients were married and 14.8% of patients were nulliparous ,history of lactation was recorded in 75.8% of patients, family history of cancer was positive in 23.5% of patients , clinically the most common presenting symptom was breast lumps 68.9% of patients followed by skin changes 13.6% of patients, skin ulceration 1.1% of patients, bloody nipple discharge 6.8% of patients, bilateral breast involvement was encountered in 1.5% of patients,8.7% of patients had palpable axillary lymph nodes ,82.6% of patients had invasive ductal carcinoma followed by 12.9% of patients had lobular carcinoma and 81.8% of patients presented with grade II cancer. Conclusion: a considerable proportion of breast cancer patients in Iraq still present with locally advanced disease at the time of diagnosis that justifies the necessity to promote public awareness educational campaigns to strengthen our national early detection program.
Downloads
References
1. Ferlay J, Colombet M, Soerjomataram I, Mathers C, Parkin D, Piñeros M, et al. Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods. International Journal of Cancer. 2019;144(8):1941–1953.
2. World Health Organization. Strategy for Cancer Prevention and Control in the Eastern Mediterranean Region 2009–2013. WHO; 2010.
3. Kulhánová I, Bray F, Fadhil I, Al-Zahrani AS, El-Basmy A, Anwar WA, et al. Profile of cancer in the Eastern Mediterranean region: The need for action. Cancer Epidemiology. 2017;47:125–132.
4. Alwan N, Al Attar W, Eliessa R, Madfaic Z, Tawfeeq F. Knowledge, attitude and practice regarding breast cancer and breast self-examination among a sample of the educated population in Iraq. 2012.
5. Alwan N. Breast cancer: demographic characteristics and clinico-pathological presentation of patients in Iraq. 2010.
6. Alwan N, Tawfeeq F, Maallah M, Sattar S, Saleh W. The stage of breast cancer at the time of diagnosis: correlation with the clinicopathological findings among Iraqi patients. Journal of Neoplasm. 2017;2(3):22.
7. Alwan N, Mualla F, Al MN, Kathum S, Tawfiq F, Nadhir S. Clinical and pathological characteristics of triple positive breast cancer among Iraqi patients. Gulf Journal of Oncology. 2017;1(25):51–60.
8. Alwan N. Iraqi initiative of a regional comparative breast cancer research project in the Middle East. Journal of Cancer Biology Research. 2014;2(1):1016.
9. Vainio H, Bianchini F. IARC Handbook of Cancer Prevention, Vol. 7: Breast Cancer Screening. Lyon, France: IARC Press; 2002.
10. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Cancer incidence and mortality worldwide. International Agency for Research on Cancer. 2013;120–163.
11. Porter P. “Westernizing” women’s risks? Breast cancer in lower-income countries. New England Journal of Medicine. 2008;358(3):213–216.
12. Alwan N, Kerr D. Cancer control in war-torn Iraq. The Lancet Oncology. 2018;19(3):291–292.
13. Alwan NA. Breast cancer among Iraqi women: preliminary findings from a regional comparative breast cancer research project. Journal of Global Oncology. 2016;2(5):255–258.
14. Alwan N, Tawfeeq F, Maallah M. The stage of breast cancer at the time of diagnosis: correlation with clinicopathological findings among Iraqi patients. Journal of Neoplasm. 2017;2(3):22.
15. Al Alwan NA. Establishing national guidelines for early detection of breast cancer in Iraq: clinical implications and perspectives. International Journal. 2015;3(12):539–555.
16. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide. CA: A Cancer Journal for Clinicians. 2018;68(6):394–424.
17. Cooper K. Pathophysiology Made Incredibly Easy. Springhouse Corporation; 1998.
18. Edge SB, Byrd DR, Carducci MA, Compton CC, Fritz A, Greene F. AJCC Cancer Staging Manual. New York: Springer; 2010.
19. Braithwaite D, Miglioretti DL, Zhu W, Demb J, Trentham-Dietz A, Sprague BL, et al. Family history and breast cancer risk among older women. JAMA Internal Medicine. 2018;178(4):494–501.
20. Alwan NA, Tawfeeq FN, Mallah NA. Demographic and clinical profiles of female patients diagnosed with breast cancer in Iraq. Journal of Contemporary Medical Sciences. 2019;5(1):14–19.
21. Velappan A, Shanmugam D. Analysis of demographic characteristics and treatment outcome of breast cancer patients in a tertiary cancer centre. IOSR Journal of Dental and Medical Sciences. 2017;16:25–28.
22. Kroman N, Wohlfahrt J, Mouridsen HT, Melbye M. Influence of tumor location on breast cancer prognosis. International Journal of Cancer. 2003;105(4):542–545.
23. Sohn VY, Arthurs ZM, Sebesta JA, Brown TA. Primary tumor location impacts breast cancer survival. American Journal of Surgery. 2008;195(5):641–644.
24. Wu S, Zhou J, Ren Y, Sun J, Li F, Lin Q, et al. Tumor location is a prognostic factor for survival of Chinese women with T1–2N0M0 breast cancer. International Journal of Surgery. 2014;12(5):394–398.
25. Darbre PD. Recorded quadrant incidence of female breast cancer in Great Britain suggests a disproportionate increase in the upper outer quadrant. Anticancer Research. 2005;25(3C):2543–2550.
26. Kene TS, Odigie VI, Yusufu LM, Yusuf BO, Shehu SM, Kase JT. Pattern of presentation and survival of breast cancer in a teaching hospital in north-western Nigeria. Oman Medical Journal. 2010;25(2):104–109.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
