MANAGEMENT OF ORAL EPITHELIAL DYSPLASIA- A REVIEW

Authors

  • Kausalyah Krisna Malay Graduate Student, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, India Author
  • Gheena S Assistant professor, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai,India Author
  • Revathy Duraisawamy Senior Lecturer, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai,India Author
  • Dhanraj Ganapathy Professor and Head Department of Prosthodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical And Technical Sciences, Chennai – 600077 Tamil Nadu, India Author

DOI:

https://doi.org/10.61841/3fkxty87

Keywords:

oral dysplasia, premalignant condition, cryotherapy, surgical excision, leukoplakia

Abstract

Aim: To review the management strategies for the treatment of oral epithelial dysplasia.

Objective: The purpose of this review is to analyse the effectiveness of success rate of the treatments given for oral epithelial dysplasia and the cure rate.

Background: Oral epithelial dysplasia is a relatively common premalignantcondition;oral dysplasia can only be diagnosed histologically. It is usually seen in the form of leukoplakia due to its non-scrapable white patches characteristic. It is a lesion that can progress into malignancy (cancer).

Reason: At present, the only effective treatment is surgical excision for oral epithelial dysplasia, but this method has high risk of recurrence. Surgical excision of large lesion may require extensive reconstruction technique. To avoid these disadvantages, a general dental practitioner should have more knowledge about the treatments for this lesion.

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References

1. Oliveira LR, Jeffrey SS, Ribeiro-Silva A. Stem cells in oral cavity. Histol Histopathol. 2010;25:371–385. PubMed PMID: 20054808.

2. Pindborg JJ, Reichart P, Smith CJ, von der Waal I. World Health Organization: histological typing of cancer and precancer of the oral mucosa. Berlin: Springer Verlag; 1997.

3. Reibel J. Prognosis of oral pre-malignant lesions: significance of clinical, histopathological, and molecular biological characteristics. Crit Rev Oral Biol Med. 2003;14:47–62.

4. Lodi G, Sardella A, Bez C, Demarosi F, Carrassi A. Interventions for treating oral leukoplakia. Cochrane Database Syst Rev. 2006.

5. Lodi G, Sardella A, Bez C, Demarosi F, Carrassi A. Interventions for treating oral dysplasia. Cochrane Database Syst Rev. 2004;(3).

6. Jakobsen C, Sørensen JA, Kassem M, Thygesen TH. Mesenchymal stem cells in oral reconstructive surgery: systematic review of the literature. J Oral Rehabil. 2013;40:693–706. doi:10.1111/joor.12079. PubMed PMID: 23834336.

7. Choi JH, Gimble JM, Lee K, Marra KG, Rubin JP, Yoo JJ, et al. Adipose tissue engineering for soft tissue regeneration. Tissue Eng Part B Rev. 2010;16:413–426. doi:10.1089/ten.teb.2009.0544. PubMed PMID: 20166810; PubMed Central PMCID: PMC2946881.

8. Moharamzadeh K, Brook IM, Van Noort R, Scutt AM, Thornhill MH. Tissue-engineered oral mucosa: review of the scientific literature. J Dent Res. 2007;86:115–124. doi:10.1177/154405910708600203. PubMed PMID: 17251509.

9. Alsberg E, Hill EE, Mooney DJ. Craniofacial tissue engineering. Crit Rev Oral Biol Med. 2001;12:64–75. doi:10.1177/10454411010120010501. PubMed PMID: 11349963.

10. Scheller EL, Krebsbach PH, Kohn DH. Tissue engineering: state of the art in oral rehabilitation. J Oral Rehabil. 2009;36:368–389. doi:10.1111/j.1365-2842.2009.01939.x. PubMed PMID: 19228277; PubMed Central PMCID: PMC2744808.

11. Agha-Hosseini F, Moslemi E, Mirzaii-Dizgah I. Comparative evaluation of low-level laser and CO₂ laser in treatment of patients with oral lichen planus. Int J Oral Maxillofac Surg. 2012;41(10):1265–1269.

12. Fornaini C, Raybaud H, Augros C, Rocca JP. New clinical approach for use of Er:YAG laser in the surgical treatment of oral lichen planus: a report of two cases. Photomed Laser Surg. 2012;30(4):234–238.

13. de Magalhaes-Junior EB, Aciole GT, Santos NR, dos Santos JN, Pinheiro AL. Removal of oral lichen planus by CO₂ laser. Braz Dent J. 2011;22(6):522–526.

14. Hegde R, Padhye A, Sumanth S, Jain AS, Thukral N. Comparison of surgical stripping; erbium-doped: yttrium, aluminum, and garnet laser; and carbon dioxide laser techniques for gingival depigmentation: a clinical and histologic study. J Periodontol. 2013;84(6):738–748.

15. Simsek Kaya G, Yapici Yavuz G, Sumbullu MA, Dayi E. A comparison of diode laser and Er:YAG lasers in the treatment of gingival melanin pigmentation. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(3):293–299.

16. Baeder FM, Pelino JE, de Almeida ER, Duarte DA, Santos MT. High-power diode laser use on Fordyce granule excision: a case report. J Cosmet Dermatol. 2010;9(4):321–324.

17. Jerjes W, Upile T, Hamdoon Z, Al-Khawalde M, Morcos M, Mosse CA, et al. CO₂ laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation. Lasers Med Sci. 2012;27(1):169–179.

18. Deppe H, Mucke T, Hohlweg-Majert B, Hauck W, Wagenpfeil S, Holzle F. Different CO₂ laser vaporization protocols for the therapy of oral precancerous lesions and precancerous conditions: a 10-year follow-up. Lasers Med Sci. 2012;27(1):59–63.

19. Luna-Ortiz K, Campos-Ramos E, Pasche P, Mosqueda-Taylor A. Oral mucosal melanoma: conservative treatment including laser surgery. Med Oral Patol Oral Cir Bucal. 2011;16(3):e381–e385.

20. Lopez-Jornet P, Camacho-Alonso F. Comparison of pain and swelling after removal of oral leukoplakia with CO₂ laser and cold knife: a randomized clinical trial. Med Oral Patol Oral Cir Bucal. 2013;18(1):e38–44.

21. Fornaini C, Rocca JP, Merigo E, Meleti M, Manfredi M, Nammour S, et al. Low energy KTP laser in oral soft tissue surgery: a 52-patient clinical study. Med Oral Patol Oral Cir Bucal. 2012;17(2):e287–e291.

22. Boj JR, Poirier C, Espasa E, Hernandez M, Espanya A. Lower lip mucocele treated with an erbium laser. Pediatr Dent. 2009;31(3):249–252.

23. Yague-Garcia J, Espana-Tost AJ, Berini-Aytes L, Gay-Escoda C. Treatment of oral mucocele: scalpel versus CO₂ laser. Med Oral Patol Oral Cir Bucal. 2009;14(9):e469–e474.

24. Lai JB, Poon CY. Treatment of ranula using carbon dioxide laser—case series report. Int J Oral Maxillofac Surg. 2009;38(10):1107–1111.

25. Lindenmuller IH, Noll P, Mameghani T, Walter C. CO₂ laser-assisted treatment of a giant pyogenic granuloma of the gingiva. Int J Dent Hyg. 2010;8(3):249–252.

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Published

14.12.2019

Issue

Vol. 23 No. 6 (2019): 23 (6) 2019

Section

Articles

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How to Cite

Krisna Malay, K., S, G., Duraisawamy, R., & Ganapathy, D. (2019). MANAGEMENT OF ORAL EPITHELIAL DYSPLASIA- A REVIEW. International Journal of Psychosocial Rehabilitation, 23(6), 1428-1433. https://doi.org/10.61841/3fkxty87