Analgesic Efficacy of Piroxicam Compared to Paracetomol in the Treatment of Post Extraction Dental Pain

Authors

  • Yashila Periasamy Undergraduate student, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai Author
  • Jagdish Kumar Senior Lecturer, Department of Oral Surgery, Saveetha Dental College,Saveetha Institute of Medical and Technical Sciences, Chennai Author
  • Dhanraj Ganapathy Professor &Head, Department of Prosthodontics, Saveetha Dental College,Saveetha Institute of Medical and Technical Sciences, Chennai Author

DOI:

https://doi.org/10.61841/hgjfsr56

Keywords:

Piroxicam, Paracetamol, Post-operative extractions

Abstract

Paracetomol is an NSAID with only analgesic properties it doesn’t relieve inflammatory pain.The analgesic activity of piroxicam, a well-known NSAID has been documented in many pain states. The purpose of this study was to assess the efficacy and the rapidity of action of piroxicam in comparison with standard paracetamol following surgical extraction of teeth.The aim of the study was to compare the efficacy and rapidity of action of piroxicam and paracetamol in the treatment of post extractive dental pain The study consisted of 30 patients of both sexes and in good health. Patient seeking dental extraction were included in this study. They were specifically selected on the criteria of reporting to Saveetha dental college and hospitals for tooth extractions only. Each participant was given a brief explanation of the study, and informed consent was obtained from each participant before inclusion in the study.From the result of this study, it is clearly evident that patient who received piroxicam has less dental pain when compared with patient who received paracetamol. This will help clinicians in prescribing medication after dental extraction.

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References

[1] Seymour RA, Blair GS, Wyatt FA. Post-operative dental pain and analgesic efficacy. Br J Oral Surg. 1983 Dec;21(4):290-7.

[2] Austrup ML, Korean G. Analgesic agents for the postoperative period: opioids. Surgical Clinics of North America. 1999 Apr 1;79(2):253-73.

[3] Rauf A, Jehan N, Ahmad Z, Mubarak MS. Analgesic Potential of Extracts and Derived Natural Products from Medicinal Plants. In Pain Relief-From Analgesics to Alternative Therapies 2017. InTech.

[4] McQuay HJ, Moore RA. An evidence-based resource for pain relief. Oxford University Press, USA; 1998.

[5] Barden J, Edwards JE, McQuay HJ, Wiffen PJ, Moore RA. Relative efficacy of oral analgesics after third molar extraction. British dental journal. 2004 Oct 9;197(7):407.

[6] Derry CJ, Derry S, Moore RA, McQuay HJ. Single dose oral ibuprofen for acute postoperative pain in adults. The Cochrane database of systematic reviews. 2009(3):CD001548.

[7] M. HariPriya, Santhosh Kumar. Dental Extraction – Post Operative wellness Survey. International Journal of PharmTech Research. 2015;8(4):666-669.

[8] Tinesh Dayaa Rao, MP Santosh Kumar. Analgesic efficacy of paracetamol vs ketorolac after dental extraction. International Journal for Research Trends and Innovation. 2018; 2(12):2456-3315.

[9] Moore A, Collins S, Carroll D, McQuay H, Edwards J. Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain. Cochrane Database Syst Rev. 2000;2:CD001547.

[10] Moore A, Collins S, Carroll D, McQuay H. Paracetamol with and without codeine in acute pain: a quantitative systematic review. Pain 1997;70:193-201.

[11] Weil K, Hooper L, Afzal Z, Esposito M, Worthington HV, van Wijk AJ, Coulthard P. A comparative study of the effect of one-suture and suture-less techniques on post-operative complications following third molar surgery. 2017;212(5):E9.

[12] Dear JW, Antoine DJ, Park BK. Where are we now with paracetamol. BMJ 2015;10:351.

[13] Brown ST, Kirkpatrick MK, Swanson MS, McKenzie IL. Pain experience of the elderly. Pain Management Nursing. 2011 Dec 1;12(4):190-6.

[14] Battisti WP, Katz NP, Weaver AL, Matsumoto AK, Kivitz AJ, Polis AB, Geba GP. Pain management in osteoarthritis: a focus on onset of efficacy—a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials. The Journal of Pain. 2004 Nov 1;5(9):511-20.

[15] Ong CK, Seymour RA, Lirk P, Merry AF. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. Anesthesia & Analgesia. 2010 Apr 1;110(4):1170-9.

[16] Hyllested M, Jones S, Pedersen JL, Kehlet H. Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. British Journal of Anaesthesia. 2002 Feb 1;88(2):199-214.

[17] Gunusen I, Karaman S, Acar A, Sargin A, Firat V. The efficacy of paracetamol versus tenoxicam on postoperative pain and morphine consumption after abdominal hysterectomy: a placebo-controlled, randomized study. Clin Exp Obstet Gynecol. 2012 Jan 1;39(1):49-52.

[18] Graziani F, Corsi L, Fornai M, Antonioli L, Tonelli M, Cei S, Colucci R, Blandizzi C, Gabriele M, Del Tacca M. Clinical evaluation of piroxicam-FDDF and azithromycin in the prevention of complications associated with impacted lower third molar extraction. Pharmacological Research. 2005 Dec 1;52(6):485-90.

[19] Toms L, Derry S, Moore RA, McQuay HJ. Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults. The Cochrane database of systematic reviews. 2009(1):CD001547.

[20] Bulley S, Derry S, Moore RA, McQuay HJ. Single dose oral rofecoxib for acute postoperative pain in adults. The Cochrane database ofsystematic reviews. 2009(4):CD004604.

[21] Nagendran M, Pereira TV, Kiew G, Altman DG, Maruthappu M, Ioannidis JP, McCulloch P. Very large treatment effects in randomised trials as an empirical marker to indicate whether subsequent trials are necessary: meta-epidemiological assessment. BMJ. 2016 Oct 27;355:i5432.

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Published

09.12.2019

How to Cite

Periasamy, Y., Kumar, J., & Ganapathy , D. (2019). Analgesic Efficacy of Piroxicam Compared to Paracetomol in the Treatment of Post Extraction Dental Pain. International Journal of Psychosocial Rehabilitation, 23(6), 1204-1209. https://doi.org/10.61841/hgjfsr56