RECURRENCE OF ORAL CANCER FOLLOWING TREATMENT IN AN INSTITUTIONAL SET UP - A RETROSPECTIVE ANALYSIS OF THE ASSOCIATED FACTOR
DOI:
https://doi.org/10.61841/yqfkem72Keywords:
Laryngeal cancer, Recurrence, TumourAbstract
Incidence of cancers of the oral cavity is increasing and has replaced laryngeal cancer as the most frequently occurring cancer in the head and neck area. Routine follow up is must for a period of 6 months to 1 year after treatment. Current guidelines advocate a follow-up period of at least 5 years to evaluate the time of recurrence following the treatment of oral cancer. Data samples required for study were taken from hospital records. All the collected data were cross verified and compiled together in an excel sheet. Compiled data were statistically analysed in SPSS software. In this study, a total of 51 patients with oral cancer had undergone treatment. 74.51% of patients reported back without any recurrence after a follow-up period of 6 months to 1 year. On associating recurrence with age it was noted that the recurrence was more in higher age groups p value of 0.025. Recurrence was common in males than females with p value of 0.025 (<0.05). To conclude, the majority of the patients in the study had no recurrence following treatment in the above follow-up period.
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[1] Bagan JV, Scully C. Recent advances in Oral Oncology 2007: epidemiology, etiopathogenesis, diagnosis and prognostication. Oral Oncol [Internet]. 2008 Feb;44(2):103–8. Available from: http://dx.doi.org/10.1016/j.oraloncology.2008.01.008
[2] van Dijk BAC, Brands MT, Geurts SME, Merkx MAW, Roodenburg JLN. Trends in oral cavity cancer incidence, mortality, survival and treatment in the Netherlands. Int J Cancer [Internet]. 2016 Aug 1;139(3):574–83. Available from: http://dx.doi.org/10.1002/ijc.30107
[3] Rogers SN, Brown JS, Woolgar JA, Lowe D, Magennis P, Shaw RJ, et al. Survival following primary surgery for oral cancer. Oral Oncol [Internet]. 2009 Mar;45(3):201–11. Available from: http://dx.doi.org/10.1016/j.oraloncology.2008.05.008
[4] Johnson FE, Maehara Y, Browman GP, Margenthaler JA, Audisio RA, Thompson JF, et al. Patient Surveillance After Cancer Treatment [Internet]. Springer Science & Business Media; 2013. 538 p. Available from: https://play.google.com/store/books/details?id=ZcZDAAAAQBAJ
[5] McGarry GW, Mackenzie K, Periasamy P, McGurk F, Gatehouse S. Multiple primary malignant tumours in patients with head and neck cancer: the implications for follow-up. Clin Otolaryngol Allied Sci [Internet]. 1992;17(6):558–62. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2273.1992.tb01718.x
[6] Curtis RE. New Malignancies Among Cancer Survivors: SEER Cancer Registries, 1973–2000 [Internet]. U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute; 2006. Available from: https://play.google.com/store/books/details?id=z28dJN3EdAYC
[7] Coviello V, Boggess M. Cumulative Incidence Estimation in the Presence of Competing Risks. Stata J [Internet]. 2004 Jun 1;4(2):103–12. Available from: https://doi.org/10.1177/1536867X0400400201
[8] Jesudasan JS, Wahab PA, Sekhar MM. Effectiveness of 0.2% chlorhexidine gel and a eugenol-based paste on postoperative alveolar osteitis in patients having third molars extracted: a randomised controlled clinical trial. Br J Oral Maxillofac Surg. 2015 Nov;53(9):826–30.
[9] Santhosh Kumar MP, Rahman R. Knowledge, awareness, and practices regarding biomedical waste management among undergraduate dental students. Asian J Pharm Clin Res. 2017;10(8):341–5.
[10] Christabel A, Anantanarayanan P, Subash P, Soh CL, Ramanathan M, Muthusekhar MR, Narayanan V. Comparison of pterygomaxillary dysjunction with tuberosity separation in isolated Le Fort I osteotomies: a prospective, multi-centre, triple-blind, randomized controlled trial. Int J Oral Maxillofac Surg. 2016 Feb;45(2):180–5.
[11] Marimuthu M, Andiappan M, Wahab A, Muthusekhar MR, Balakrishnan A, Shanmugam S. Canonical Wnt pathway gene expression and their clinical correlation in oral squamous cell carcinoma. Indian J Dent Res. 2018 May;29(3):291.
[12] Packiri S, Gurunathan D, Selvarasu K. Management of paediatric oral ranula: a systematic review. J Clin Diagn Res. 2017 Sep;11(9):ZE06.
[13] Santhosh Kumar MP. Relationship between dental anxiety and pain experience during dental extractions. Asian J Pharm Clin Res. 2017;10(3):458–61.
[14] Patil SB, Durairaj D, Kumar GS, Karthikeyan D, Pradeep D. Comparison of extended nasolabial flap versus buccal fat pad graft in the surgical management of oral submucous fibrosis: a prospective pilot study. J Maxillofac Oral Surg. 2017 Sep;16(3):312–21.
[15] Rao TD, Santhosh Kumar MP. Analgesic efficacy of paracetamol vs ketorolac after dental extractions. Res J Pharm Technol. 2018;11(8):3375–9.
[16] Abhinav RP, Selvarasu K, Maheswari GU, Taltia AA. The patterns and etiology of maxillofacial trauma in South India. Ann Maxillofac Surg. 2019 Jan;9(1):114.
[17] Santhosh Kumar MP, Sneha S. Knowledge and awareness regarding antibiotic prophylaxis for infective endocarditis among undergraduate dental students. Asian J Pharm Clin Res. 2016;9:154–9.
[18] Santhosh Kumar MP. The emerging role of botulinum toxin in the treatment of orofacial disorders: Literature update. Asian J Pharm Clin Res. 2017;10(9):21–9.
[19] Rahman R, Santhosh Kumar MP. Knowledge, attitude, and awareness of dental undergraduate students regarding HIV/AIDS patients. Asian J Pharm Clin Res. 2017;10(5):175–80.
[20] Santhosh Kumar MP, Sneha S. Knowledge and awareness regarding antibiotic prophylaxis for infective endocarditis among undergraduate dental students. Asian J Pharm Clin Res. 2016;9:154–9.
[21] Patturaja K, Pradeep D. Awareness of basic dental procedure among general population. Res J Pharm Technol. 2016;9(9):1349–51.
[22] Jain SV, Muthusekhar MR, Baig MF, Senthilnathan P, Loganathan S, Wahab PA, Madhulakshmi M, Vohra Y. Evaluation of three-dimensional changes in pharyngeal airway following isolated Lefort one osteotomy for correction of vertical maxillary excess: a prospective study. J Maxillofac Oral Surg. 2019 Mar;18(1):139–46.
[23] Pagh A, Grau C, Overgaard J. A longitudinal study of follow-up activities after curative treatment for head and neck cancer. Acta Oncol [Internet]. 2015 May;54(5):813–9. Available from: http://dx.doi.org/10.3109/0284186X.2015.1028591
[24] Wang B, Zhang S, Yue K, Wang X-D. The recurrence and survival of oral squamous cell carcinoma: a report of 275 cases. Chin J Cancer [Internet]. 2013 Nov;32(11):614–8. Available from: http://dx.doi.org/10.5732/cjc.012.10219
[25] Lindenblatt R de CR, Martinez GL, Silva LE, Faria PS, Camisasca DR, Lourenço S de QC. Oral squamous cell carcinoma grading systems—analysis of the best survival predictor. J Oral Pathol Med [Internet]. 2012;41(1):34–9. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0714.2011.01068.x
[26] Ebrahimi A, Clark JR, Zhang WJ, Elliott MS, Gao K, Milross CG, et al. Lymph node ratio as an independent prognostic factor in oral squamous cell carcinoma. Head Neck [Internet]. 2011 Sep;33(9):1245–51. Available from: http://dx.doi.org/10.1002/hed.21600
[27] Vázquez-Mahía I, Seoane J, Varela-Centelles P, Tomás I, Álvarez García A, López Cedrún JL. Predictors for tumor recurrence after primary definitive surgery for oral cancer. J Oral Maxillofac Surg [Internet]. 2012 Jul;70(7):1724–32. Available from: http://dx.doi.org/10.1016/j.joms.2011.06.228
[28] de Vicente JC, Rodríguez-Santamarta T, Rosado P, Peña I, de Villalaín L. Survival after free flap reconstruction in patients with advanced oral squamous cell carcinoma. J Oral Maxillofac Surg [Internet]. 2012 Feb;70(2):453–9. Available from: http://dx.doi.org/10.1016/j.joms.2011.02.020
[29] Farhat Yaasmeen Sadique Basha, Rajeshkumar S, Lakshmi T. Anti-inflammatory activity of Myristica fragrans extract. Int J Res Pharm Sci. 2019;10(4):3118–20. DOI: https://doi.org/10.26452/ijrps.v10i4.1607
[30] Capote A, Escorial V, Muñoz-Guerra MF, Rodríguez-Campo FJ, Gamallo C, Naval L. Elective neck dissection in early-stage oral squamous cell carcinoma—does it influence recurrence and survival? Head Neck [Internet]. 2007;29(1):3–11. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/hed.20482
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