Electrolyte Disturbance among Hypertensive Patient In Baquba teaching hospital , Diyala , Iraq
DOI:
https://doi.org/10.61841/0621gs71Keywords:
Hypertension, Electrolyte disturbance, Diabetes, Ischemic heart disease,, Sodium, , Potassium Magnesium,, calcium .Abstract
T Hypertension attack about ¼ of adult’s people all over the world, this attack come from the internal and external surrounding environment. Electrolyte imbalances are common findings in many diseases Sodium, potassium, calcium, and other ions should be balanced and any change in ions value must take inconsideration as a colligative and associated style, any investigation have to stress of understanding of clinical scenario searching on successful and effective therapy. In this study we took these electrolyte and study their disturbance in the hypertensive patient and connect it to other disorders like diabetes and IHD.
A case – control study was done in Ba’quba Teaching hospital , Diyala , Iraq during the period of 16th of septemper 2018 – 3rd of January 2019 on one hundred primary person were included in our study , Eighty one were the cases who have hypertension ( 55 female and 25 male ) compared to a twenty healthy person” Control” ( 11 female and 10 male ) which the take information by questionnaire then aspirate blood and send for investigation (Na, Cl , K , Ca , Phosphorus , B.Urea , S.Creatinine , RBS And HBA1c )
Then classify them into three groups : first who had hypertension and IHD only , second who had Hypertension and Diabetes and third group who had Hypertension , Diabetes and IHD .
The result of our study demonstrate that the first group had a significant reduce in serum magnesium and increase of serum NaCl , the second group demonstrate that there is significant reducing in serum Mg++ , Ca++ and K+ and increase in serum Nacl , third group demonstrates significant reducing of serum Mg++..
In this study we demonstrate a significant reduction in both serum magnesium and calcium levels among patients with hypertension , diabetes, and significant inverse correlation of both serum magnesium and calcium with hypertension ,diabetes and cardiovascular diseases
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1. 1. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365:217-223
2. 2. Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ. Selected major risk factors and global and regional burden of disease. Lancet 2002;360:1347-1360
3. 3. Kaplan NM. Primary hypertension: pathogenesis. In: Kaplan NM, ed. Kaplan's clinical hypertension. 9th ed. Philadelphia: Lippincott Williams & Wilkins, 2006:50-121.
4. 4. Williams GH, Hollenberg NK. Non-modulating hypertension: a subset of sodium-sensitive hypertension. Hypertension 1991;17:Suppl 1:I81-I85
5. 5. O'Shaughnessy KM, Karet FE. Salt handling and hypertension. J Clin Invest 2004;113:1075-1081
6. 6. Elliott P. Salt and blood pressure. In: Izzo JL Jr, Black HR, eds. Hypertension primer. 3rd ed. Dallas: American Heart Association/Council on High Blood Pressure Research, 2003:277-9.
7. 7. Iwamoto T, Kita S. Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPase. Kidney Int2006;69:2148-2154
8. 8. Whelton PK. Potassium and blood pressure. In: Izzo JL Jr, Black HR, eds. Hypertension primer. 3rd ed. Dallas: American Heart Association/Council on High Blood Pressure Research, 2003:280-2.
9. 9. Molecular Aspects of Medicine Volume 24, Issues 1–3, 6 February 2003, Pages 107-136
10. 10. Messerli FH, Williams B, Ritz E. Essential hypertension. Lancet. 2007;370:591–603. doi: 10.1016/S0140-6736(07)61299-9
11. 11. Lee CT, Guo HR, Chen JB. Hyponatremia in the emergency department. Am J Emerg Med 2000; 18: 264–268.
12. 12. Shiber JR, Mattu A. Serum phosphate abnormalities in the emergency department. J Emerg Med 2002; 23: 395–400.
13. 13. H, Fujimaki H, Inoue J, Shiraki M. Disorders of fluid and electrolyte metabolism in elderly diabetics. Nihon Ronen Igakkai Zasshi 1989; 26: 233–239.
14. 14. Goldberg A, Hammerman H, Petcherski S, Zdorovyak A, Yalonetsky S, Kapeliovich M, et al. Prognostic importance of hyponatremia in acute ST-elevation myocardial infarction. Am J Med 2004; 117: 242–248.
15. 15. Goldberg A, Hammerman H, Petcherski S, Nassar M, Zdorovyak A, Yalonetsky S, et al. Hyponatremia and long-term mortality in survivors of acute ST-elevation myocardial infarction. Arch Intern Med 2006.
16. 16. Packer M. Neurohormonal interactions and adaptations in congestive heart failure. Circulation 1988; 77(4):721–730.
17. 17. Leier CV, Dei CL, Metra M. Clinical relevance and management of the major electrolyte abnormalities in congestive heart failure: hyponatremia, hypokalemia, and hypomagnesemia. Am Heart J 1994; 128(3):564–574.
18. 18. Dei CL, Metra M, Leier CV. Electrolyte disturbances in chronic heart failure: metabolic and clinical aspects. Clin Cardiol 1995; 18(7):370–376.
19. 19. Resnick LM, Gupta RK, Bhargava KK, Gruenspan H, Alderman MH, Laragh JH. Cellular ions in hypertension, diabetes, and obesity. A nuclear magnetic resonance spectroscopic study. Hypertension 1991; 17(6 Pt 2):951–957.
20. 20. Resnick LM, Barbagallo M, Dominguez LJ, Veniero JM, Nicholson JP, Gupta RK. Relation of cellular potassium to other mineral ions in hypertension and diabetes. Hypertension 2001; 38(3 Pt 2):709–712.
21. 21. Whang R, Oei TO, Aikawa JK, Watanabe A, Vannatta J, Fryer A, Markanich M. Predictors of clinical hypomagnesemia. Hypokalemia, hypophosphatemia, hyponatremia, and hypocalcemia. Arch Intern Med 1984; 144(9):1794–1796.
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