AWARENESS OF CLINICAL APPLICATIONS OF VITAMIN K AMONG DENTAL STUDENTS
DOI:
https://doi.org/10.61841/km2fzh32Keywords:
Vitamins, Bleeding, toxicity, fruits, vegetables, haemorrhage, coagulationAbstract
Background: Vitamin K was first identified in 1936 to be a key factor in blood clotting. When chickens were fed a low-fat diet, they exhibited significantly lower coagulation capacity, resulting in severe bleeding. The lipid fraction of diet was analyzed, and a novel antihemorrhagic factor was discovered. This lipid-soluble factor was given the first letter in the alphabet available, which coincided with the first letter of the German word koagulation, and was deemed to be only essential for its anti-haemorrhagic trait. Since then, non-coagulant functions have been discovered and have attracted research interest in several fields around the world. Vitamin K occurs as two vitamins: vitamin K1 (also known as phylloquinone) and vitamin K2 (designated also as menaquinones (MKs). AIM: To evaluate and compare the awareness of clinical application of vitamin K among dental students. MATERIALS AND METHODS A cross-sectional survey was carried among 100 dental practitioners using a questionnaire. Questionnairecontained 10 questions on awareness of clinical applications of vitamin E among dental students. The data were extracted and analysed. Conclusion: The purpose of the study is to create awareness of clinical applications of vitamin K among dental students.
Downloads
References
2. Lussier G, Loew FM.Case report. Natural Hymenolepis nana infection in mongolian gerbils (Merionesunguiculatus). Can Vet J. 1970;11(5):105-7. pmid: 5464373.
3. McDonald J. Dietary and nutritional influences on dental caries. Nutrition inoral health and disease. Philadelphia: LeaandFebiger; 1985. p. 151-60.
4. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C.The global burden of oral diseases and risks tooral health. Bull World Health Organ. 2005;83(9):661-9. pmid: 16211157.
5. Neha Bansal ND. Impact of micronutrients on oral health. Excel Int JEduc Res. 2014;2(1):89-102.
6. Thomas AG. Vitamins and trace elements. CurrPaediatr 1992;2(3):172-4. doi: 10.1016/0957-5839(92)90259-t.
7. Kathariya R, Kulkarni N, Kulkarni M, Kalele K. Trace elements in oral health and disease: An updated review. J Dent Res Rev. 2014;1(2):100. doi: 10.4103/2348-2915.13 3959.
8. Ghosh A. Role of Vitamins in Oral Health & Disease: an Overview. Indian JAppl Res. 2015;5(12):292-5.
9. Harris R. Dietary Chemicals vs. Dental Caries. Am Chem Soc. 1970;94:33-45.
10. Dam, H.; Schønheyder, F. The occurrence and chemical nature of vitamin K. Biochem. J. 1936, 30, 897–901. [CrossRef] [PubMed]
11. Shenkin, A. Dietary reference values for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J. Hum. Nutr. Diet. 2003, 16, 199–200. [CrossRef]
12. Schwalfenberg, G.K. Vitamins K1 and K2: The Emerging Group of Vitamins Required for Human Health. J. Nutr. Metab. 2017, 2017, 6254836. J. Nutr. Metab. 2017, 2017, 6254836. [CrossRef] [PubMed]
13. Gröber, U.; Reichrath, J.; Holick, M.F.; Kisters, K. Vitamin K: An old vitamin in a new perspective. Dermato-Endocrinology 2015, 6, e968490.
14. Shearer, M.J.; Newman, P. Metabolism and cell biology of vitamin K. Thromb. Haemost. 2017, 100, 530–547.
15. Schurgers, L.J.; Vermeer, C. Determination of Phylloquinone and Menaquinones in Food. Pathophysiol. Haemost. Thromb. 2001, 30, 298–307. [CrossRef] [PubMed]
16. Gijsbers, B.L.M.G.; Jie, K.-S.G.; Vermeer, C. Effect of food composition on vitamin K absorption in human volunteers. Br. J. Nutr. 2007, 76, 223–229. volunteers. Br. J. Nutr. 2007, 76, 223–229. [CrossRef]
17. Madrid C, Sanz M. What influence do anticoagulants have on oral implant therapy? A systematic review. Clin Oral Implants Res. 2009;20:96-106.
18. Abayon M, Kolokythas A, Harrison S, Elad S. Dental management of patients on direct oral anticoagulants: case series and literature review. Quintessence Int. 2016;47:687-96.
19. Firriolo FJ and Hupp WS. Beyond warfarin: the new generation of oral anticoagulants and their implications for the management of dental patients. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:431-41.
20. O’Conell JH. New oral anticoagulants and their implications for dental patients. J Ir Dent Assoc. 2014;60:137-43.
21. Krishnan B, Shenoy NA, Alexander M. Exodontia and Antiplatelet Therapy. J Oral Maxillofac
Downloads
Published
Issue
Section
License
Copyright (c) 2020 AUTHOR

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.