Anthelmithic activity of Methanolic extract of Phaseolus semierectus (L.)
DOI:
https://doi.org/10.61841/ppb5sx41Keywords:
Phaseolus semierectus (L.)., Anthelmintic activity, Piperazine citrateAbstract
Phaseolus semierectus (L.). is the most significant genus in the family Fabaceae, which is commonly known as Purple been in India1. This study evaluates anthelmintic activity of methanol extract of Phaseolus semierectus (L.). on Indian adult earthworms, Pheretima posthuma (annelid).Aerial parts were extracted by using soxhlet apparatus. Phytochemical screening of crude extracts showed the presence of Alkaloids, Tannins, phenolics, flavanoids, terpenoids, steroids and proteins2. Various concentrations (25, 50, 100mg/ml) of crude extracts were tested for anthelminthic activity when involved the determination of the time of paralysis and time of death of worms. The activity was compared with standard piperazine citrate. The methanolic extract shows significant activity when compared to the standard piperazine citrate. The paralysis and death time is 56, 32, 18 and 77, 53, 34 minutes respectively at concentrations 25, 50 and 100mg/ml. whereas these are 31, 18, 10 and 63, 41, 22 minutes for piperazine citrate. In order to confirm the studies in vivo studies have to be conducted.
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1. Marechal R, Mascherpa JM, Stainer F. (1978).Etude taxonomique d’un groupe complexe d’especes des genres Phaseolus et Vigna (Papilionaceae) sur la base de donnees morphologiques. Boissiera, ;( 28): 1– 273.
2. Madhava CK, Sivaji K,Tulasi RK. (2008).Flowering plants of Chittoor district,Andhra predesh,(1): 101.
3. Oomah BD, Corbé A, Balasubramanian P. (2010).Antioxidant and anti-inflammatory activities of bean (
Phaseolus vulgaris L.) hulls. J. Agric Food Chem. ;58(14):8225-30
4. Ocho-Anin Atchibri AL, Brou KD, Kouakou TH, Kouadio YJ, Gnakri D. (2010).Screening for antidiabetic activity and phytochemical constituents of common bean (Phaseolus vulgaris L.) seeds J. Medicl Plant Rese;4(17):1757-1761
5. Ocho-Anin Atchibri AL, Kouakou TH. (2010).Evaluation of bioactive components in seeds of
Phaseolusvulgaris L. (fabaceae) cultivated in Côte d’Ivoire2010.J. Appl. Biosci 31:1928-34.
6. Azevedo L, Gomes JC, Stringheta PC, Gontijo AMMC, Padovani CR, Ribeiro LR, Salvadori DMF. (2003).Black bean (Phaseolus vulgaris L.) as a protective agent against DNA damage in mice. Food Chem Toxicol. ; 41:1671–1676.
7. Chan YS, Wong JH, Fang EF, Pan WL, Ng TB. (2012).An antifungal peptide from Phaseolus vulgaris cv. brown kidney bean. Acta Biochim Biophys Sin;44(4):307-15.
8. Ye XY, Ng TB, Tsang PW,Wang J. (2001).Isolation and homodimeric lectin with antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds. J. Protein Chem; 20, 367–375.
9. Mauro AMC, Noemi F, Barbara L, Giancarlo C, Gian Luigi G. (2011).Multiple cycles of repeated treatments with a Phaseolus vulgaris dry extract reduce food intake and body weight in obese rats British Journal of Nutrition; 1- 7.
10. Solanki YB, Jain SM. (2010).Immunostimolatory activities of Vigna mungo L. extract in male Sprague- Dawley rats. J. Immunotoxicol;7(3):213-8.
11. Hepper AG, Mital K, Sheth NR, Dudhrejiya AV. (2011).Anticonvulsant activity of extract from the seeds of Vigna mungo (L.). J.Pharmacy Research.;4 (6):1943-48.
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