EVALUATION OF ANTIOXIDANT AND ANTI-CHOLESTEROL ACTIVITY OF ETHANOLIC LEAF EXTRACT OF GYMNEMA SYLVESTRE – AN IN VITRO STUDY
DOI:
https://doi.org/10.61841/22cdbd43Keywords:
antioxidant, ,anti-cholesterol activity ethanolic leaf extract Gymnema sylvestre, An in vitro studyAbstract
Gymnema sylvestre, which is extensively used for serving as traditional remedy for various ailments like diabetes and malaria, belongs to the family Asclepiadaceae and genus gymnema. Recent research has proved that Gymnema can be used as a supplement in the treatment of both type 1 and type 2 diabetes mellitus. Since the herb has potential anti diabetic property research can be done to evaluate its anti-cholesterol and antioxidant potential.Antioxidant and anticholesterol potential of ethanolic leaf extract of the Gymnema sylvestre plant was investigated.The Gymnema sylvestre leaf extract showed a good free radical scavenging activity. The antioxidant potential is comparable to that of VIT C. High cholesterol levels in blood is one of the causes of deadly cardiovascular disease. The result exhibited is the significant anti-cholesterol property of plant extract.From this study, it can be concluded that the Gymnema sylvestre leaf extract possess antioxidant and anti-cholesterol activity. Further in vivo studies can be done so that the extract can be made into a drug.
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References
1. Arya Vaidya Shala, “Indian Medicinal Plants- A Compendium of 500 species”, 1997
2. N. Ramadass, N. Subramanian, R. Ponnulakshmi, J. Selveraj, “Phytochemical Screening and Antibacterial Activity of Leaf Extracts of Gymnema sylvestre against Pathogenic Bacteria”, 2019, (6) 23-28
3. Tiwari P, Mishra BN, Sangwan NS "Phytochemical and pharmacological properties of Gymnema sylvestre: an important medicinal plant”, 2014
4. Patel Chirag J, Satyanand Tyagi, Nirmala Halligudi, Jaya Yadav, Sachchidanand Pathak, Satya Prakash Singh, Ashish Pandey, Darshan Singh Kamboj, Pratap Shankar, “Antioxidant Activity of herbal plants: A Recent Review”, Journal of Drug Discovery and Therapeutics 1 (8) 2013, 01-08
5. Rachh P. R., Rachh M. R., N.R. Ghadiya, D.C. Modi, K.P. Modi, N.M. Patel, M.T. Rupareliya, “Antihyperlipidemic activity of Gymnema sylvestre R. Br. leaf extract on rats fed with high cholesterol diet.”, 2010
6. Chris Noel Timothy,V.Vishnu Priya ,R.Gayathri Phytochemical analysis and total phenolic content of origanum vulgare( oregano) Drug Invention Today vol 10. Issue 10. 2018
7. Padayatty SJ, Katz A, Wang Y, Eck P, Kwon O, Lee JH, Chen S, Corpe C, Dutta A, Dutta SK, Levine M., “Vitamin C as an Antioxidant: Evaluation of its Role in Disease Prevention.” 2003; 22(1):18-35.
8. Packyanathan JS, Gayathri R, Vishnupriya V. Preliminary phytochemical analysis and cytotoxicity potential of Bacopa monnieri on oral cancer cell lines. Int J Pharm Sci Rev Res 2016;39 Article No. 02:4- 8.
9. P.R. Rachh, S.R. Patel, H.V. Hirpara, M.T. Rupareliya, M.R. Rachh, A.S. Bhargava, N.M. Patel, D.C. Modi, “In Vitro evaluation of antioxidant activity of gymnema sylvestre R. Br. Leaf extract.”, (2009)
10. Ezealisiji K M, Stanley C N, Ekanem E S, “Evaluation of Anti-Cholesterol Activity of Ethyl Acetate and N- Hexane Extracts of Tetracarpidium conophorum (Mull. Arg.) Hutch and Dalziel (African Walnut) Towards Hypercholesterolemic Rat”, International Journal of Pharmacognosy and Phytochemical Research 2016; 8(8); 1372-1376
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