Norfloxacin In Dental Practice

Abstract

Antibiotics are commonly used in dental practice. It has been estimated that 10% of all antibiotic prescriptions are related with dental infections.Periodontal disease is caused by bacteria in dental plaque, the sticky substance that forms on your teeth a couple of hours after you have brushed. Interestingly, it is your body's response to the bacterial infection that causes most of the problems. In an effort to eliminate the bacteria, the cells of your immune system release substances that cause inflammation and destruction of the gums, periodontal ligament or alveolar bone. This leads to swollen, bleeding gums, signs of gingivitis the earliest stage of periodontal disease, and loosening of the teeth, a sign of severe periodontitis the advanced stage of disease. A Method for treating or preventing periodontal disease which comprises administering nor floxacin or salts thereof locally to periodontal tissue are disclosed. The method is excellent on the treatment of periodontal disease in small dose without disturbance of bacterial flora. The rate of progression of periodontal disease in an individual is dependent on the virulence (or strength of attack) of the bacterial plaque and on the efficiency of the local and systemic immune inflammatory responses in the person (host). The overall balance between the bacterial plaque challenge and the body’s immune inflammatory responses is critical to periodontal health. The best clinical outcome for a periodontal patient following treatment would be the retention of formerly diseased teeth for a lifetime. The vast majority of gum diseases can be easily prevented by daily thorough plaque removal. However, irregularities around the teeth such as overhanging edges on fillings, poorly contoured fillings, and some types of partial denture designs make tooth cleaning difficult and encourage the accumulation of plaque. The presence of calculus (tartar) – plaque that has calcified and hardened – may also cause plaque to accumulate more readily and requires professional removal (scaling). For the majority of the population, however, periodontal health can be effectively maintained by proper oral hygiene practices as well as avoidance of behavioral and environmental risk factors (e.g., tobacco smoke, stress, poor diet) on the part of the individual. Because periodontal disease is linked to an increased susceptibility to systemic disease (e.g., cardiovascular disease, infective endocarditis, bacterial pneumonia, low birth weight, diabetes), it is important not only for oral health but also for general health to control periodontal disease.