The Relationship between Refractive Errors and Intraocular Pressure After Adjusting with Central Corneal Thickness

Authors

  • Rabeea Mifath Mohammed Juwayli Zagazig University Author

DOI:

https://doi.org/10.61841/jan47b98

Keywords:

Central corneal thickness, Intraocular pressure,, Sirius topography,, Spherical equivalent refractive error

Abstract

Background : It is generally accepted that there is an increased prevalence of glaucoma among myopic eyes. One of the reasons as to whyglaucoma should be more frequent in myopic eyes seems to be higher intraocular pressure (IOP) in myopic eyes compared with non-myopic eyes. Aim of the study: This study was aimed to assess the correlation between refractive status and intraocular pressure after adjustment with Central corneal thickness. Patients and Methods : This Prospective cross-sectional study was conducted in Ophthalmology Department at Zagazig University Hospitals. 50 patients with refractive errors, divided in 2 groups 25 are myopic eyes and 25 are hypermetropic eyes. During the period from April to December 2019, Before the experiment, all patients underwent a complete ophthalmic examination, including visual acuity, manifest refraction, comprising refraction, slit lamp examinations and corneal topography. Results: There was a statistical significant negative correlation between spherical equivalent and IOP and AIOP (r=-0.728 and r=- 0.499, P-value <0.05), regarding central corneal thickness, there was statistically significant negative correlation between AIOP and CCT(r=-0.419, p-value <0.05)but there was positive correlation between CCT and IOP(r=0.521, p-value<0.05). Conclusions: The myopic refractive error and the intra-ocular pressure seem to have a significant correlation as such that with the increase of myopic refractive error there was increase of the intra-ocular pressure. This findings support the hypothesis that the relationship between glaucoma and myopia might be pressure mediated.

 

Downloads

Download data is not yet available.

References

1. Avitabile T, Longo A, Rocca D, Amato R, Gagliano C, Castaing M. The influence of refractive errors on IOP measurement by rebound tonometry (ICare) and Goldmann applanation tonometry. Graefes Arch Clin Exp Ophthalmol 2010; 248 (4) : 585-91.

2. Han X, Yang T, Zhang J, Yu S, Guo X, Yan W. et al. Longitudinal changes in intraocular pressure and association with systemic factors and refractive error: Lingtou Eye Cohort Study. BMJ open 2018; 8 (2): e019416.

3. Sanaa AY, Elham R A. Age, gender and refractive error association with intraocular pressure in healthy Saudi participants: A cross-sectional study. Saudi J Ophthalmol 2016; 30 (1): 44-48.

4. Das P, Das R, Shrivastava P, Mondal A. A clinical study on the correlation between axial length, intraocular pressure and central corneal thickness in myopic eyes. International Journal of Contemporary Medical Research 2016; 3, 1141-1144.

5. Fern K, Manny R, Gwiazda J, Hyman L, Weise K, Marsh-Tootle W. Intraocular pressure and central corneal thickness in the COMET cohort. Optom Vis Sci 2012; 89 (8): 1225-34.

6. Wei W, Fan Z, Wang L, Li Z, Jiao W, Li Y. Correlation analysis between central corneal thickness and intraocular pressure in juveniles in Northern China: the Jinan city eye study. PLoS On e 2014; 9(8): e104842

7. Wang S, Melles R, Lin S. The impact of central corneal thickness on the risk for glaucoma in a large multiethnic population. J Glaucoma 2014; 23 (9): 606–612..

8. Jorge J, Rosado J, Diaz-Rey J, González-Méijome J. Central corneal thickness and anterior chamber depth measurement by Sirius Scheimpflug tomography and ultrasound. Clin Ophthalmol 2013; 7:417– 422.

9. Shah S, Spedding C, Bhojwani R, Kwatz J, Henson D, Mcleod D. Assessment of the diurnal variation in central corneal thickness and intraocular pressure for patients with suspected glaucoma. Ophthalomology 2000; 107 (6) :1191-1193.

10. Natung T, Taye T, Lyngdoh L, Dkhar B, Hajong R. Refractive errors among patients attending the ophthalmology department of a medical college in North-East India. J Family Med Prim Care 2017; 6 (3): 543.

11. Wong T, Klein B, Klein R, Knudtson M, Lee K. Refractive errors, intraocular pressure, and glaucoma in a white population. Ophthalmology 2003; 110 (1): 211-217.

12. Mukesh B, McCarty C, Rait J, Taylor H. Five-year incidence of open-angle glaucoma: the visual impairment project. Ophthalmology 2002; 109 (6) : 1047-1051.

13. Mitchell P, Hourihan F, Sandbach J, Wang J. The relationship between glaucoma and myopia: the Blue Mountains Eye Study. Ophthalmology 1999, 106(10): 2010-2015.

14. Mourad M, Rayhan R, Moustafa M, Hassan A. Correlation between central corneal thickness and axial errors of refraction. J Egypt Ophthalmol Soc 2019; 112(2): 52.

15. McGhee C, Ormonde S, Kohnen T, Lawless M, Brahma A, Comaish, I. The surgical correction of moderate hypermetropia: the management controversy. Br J Ophthalmol 2002, 86(7): 815-822.

16. Karthikeyan B, Meenakshi S. The results of treatment of anisomyopic and anisohypermetropic amblyopia. Int Ophthalmol 2009, 29(4): 231-7.

17. Jarade E, Nader F, Tabbara K. Intraocular pressure measurement after hyperopic and myopic LASIK. J Refract Surg 2005, 21(4), 408-410.

18. Osaiyuwu A, Edokpa G. A Comparative Study of Intra Ocular Pressure in Myopia and Hyperopia Among a Nigerian Population Just Diagnosed With Primary Open Angle Glaucoma in Benin City. Int J Res Med Sci 2018, 6: 2234-7.

19. Iyamu E, Iyamu J, Amadasun G. Central corneal thickness and axial length in an adult Nigerian population. J Optom 2013, 6 (3): 154-160.

20. Nomura H, Ando F, Niino N, Shimokata H, Miyake Y. The relationship between intraocular pressure and refractive error adjusting for age and central corneal thickness. Ophthalmic Physiol Opt 2004; 24(1): 41-45.

Downloads

Published

31.07.2020

How to Cite

Juwayli, R. M. M. (2020). The Relationship between Refractive Errors and Intraocular Pressure After Adjusting with Central Corneal Thickness. International Journal of Psychosocial Rehabilitation, 24(5), 9223-9232. https://doi.org/10.61841/jan47b98