Detection of Human Herpes Virus-6 in Children Suffering from Febrile Convulsion
DOI:
https://doi.org/10.61841/3sybfx14Keywords:
Febrile Convulsion, Human Herpes Virus-6, fit with Fever, PCRAbstract
A total of 150 blood samples were taken from children who were suffering from febrile convulsions during the period from April 2019 to October 2019 and who were admitted to Babel Hospital, Al-Noor Hospital, and Al-Imam Al-Sadiq Center at ages ranging from six months to five years old. Out of (150) blood samples, (50) samples of children who suffered from febrile convulsion fit as group one [31 male (62%) and 19 female (38%)], (50) samples of children who suffered from fever without fit as group two [34 male (68%) and 16 female (32%)], and (50) samples of control cases (healthy children) as group three [36 male (72%) and 14 female (28%)]. Demographic data of patients and controls (age, gender, weight, and residence) were studied from all blood samples taken from children. The mean of ages for the three study groups was investigated; it was found that there were no significant statistical relationships between them (P = 0.88). Distribution of study groups according to gender was studied; the results showed that there were no important variances among study groups (P = 0.56) regarding gender. According to the study of patients’ weight, there were no important statistical relationships among the study groups (P= 0.28). In this study, the distribution of patient groups according to residence was studied. It was found that there were highly significant differences (P = 0.000) in the urban area within the health group compared with the patient group. Human Herpes Virus 6 was detected from blood samples by qPCR technique. It was found that, from 50 (100%) samples of conventional febrile (fit with fever), 18 (36%) isolated were related to HHV6. In a group with fever, it was found that, from 50 (100%) samples, 12 (24%) isolates were related to this virus.
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