Thyroid dysfunction In Type 1 Diabetic Pediatric Patients And It's Relation To Diabetes Severity

Background; Type 1 diabetes (T1DM) is an autoimmune disease often associated with thyroid abnormalities. Aim and objectives: To assess the thyroid function in pediatric patients with T1DM and it's relation to diabetes severity. Subjects and methods: This is a cross section study was performed at Zagazig Univeristy hospital in diabetes clinic and Pediatric Diabetes Insurance Clinic in Sharkia Governorate,on two hundred and twelve patients, during a period from November 2019 to April 2020. Results: children who had both T1DM and hypothyroidism most of them experienced Diabetic Ketoacidosis (DKA) as the first presentation of their disease (68%) and had higher HbA1C levels (11.37 ±2.10) in comparison to (36.3%) and (10.02 ± 1.89) respectively in diabetic patients with normal thyroid function. Conclusion: Hypothyroidism is prevalent among pediatric patients with T1DM and is associated with a more aggressive form of the disease. Patients with T1DM and hypothyroidism have higher rates of DKA and develop the disease at younger ages.