Impact of (HCV) and (HBV) co-infection among HIV infected patients
Ahmed Alaa-EldinAbdelrahman Ahmed Elgayar, Ahmed Mohamed Elsheaita, Mohamed Abdel-Basset Algomaei, Saeed Abdel-Baki Gad
Background: The biggest public health problems are still HIV, HBV and HCV. These virus infections are in the top ten deaths caused by infectious diseases. The variability of HIV/hepatitis coinfection incidence in the world is complex and depends on geographical areas, risks and exposure types for infections.
Objective: To investigate HBV and HCV prevalence in HIV patients. Patients and Methods: This study was conducted on HIV infected, and AIDS patients attending Alexandria Fever Hospital during the period from August 2018 to July 2019, assuming prevalence of HCV in HIV patients is 15% sample was calculated to be 141 patients using epi info version 7 program with test power 80%, CI 95%.
Results: The incidence of infection with hepatitis C virus was 45 patients (31.9%), all the 45 tested positive for PCR for HCV RNA as HIV accelerated progression of the disease making it almost impossible for HCV spontaneous clearance. It is much higher than average people and is 9 patients with hepatitis B infection (6.4 percent ). In patients with immunodeficit the incidence of co-infection between Hepatitis C and HBV was 2,8 percent, with a combined infection in 4 of 141 patients of the three viruses.
Conclusion: The findings of current work emphasize the importance of continued HIV-positive screening for HBV and HCV markers prior to beginning HAART as this procedure could direct the right choice of medicinal combination.