A CROSS-SECTIONAL COMPARISON OF MINERALS IN PSYCHIATRIC DISORDER

The burden of mental disorders with onset in childhood and adolescence decreased by varying degrees for the individual disorders, and this decrease was generally smaller in the less developed states than in the more developed states. The increase in the burden of depressive disorders, anxiety disorders, Panic disorders, Social phobia, and bipolar disorder was driven by the ageing of the population because age-standardisation nullified this increase. To study the levels of, sodium, potassium and calcium in psychiatric disorders.The present study includes total 100 subjects were selected for study. Out of which 50 were age and sex matched normal healthy control, 50 were suffered from psychiatric disorders. Blood sample were collected, and Electrolyte levels were measured by electrolyte analyzer, as electrolyte analyzer has different electrodes, specific for different ions of interest. Each electrode has an ion selective membrane that undergoes a specific reaction with the corresponding ions contained in the sample being analyzed.In our study the mean sodium levels in cases as 131.52±2.099 and in controls it was 137.98±6.06 (P<0.0001), this was statistically significant. Mean calcium and Potassium levels in cases were 13.30±3.35 and 3.35±0.23, while in controls it was 9.44±4.40 and 3.78±0.71 respectively. These results were also found to be statistically significant.The present study showed the levels of Na, K are decreased, and Ca concentration was increased found in psychiatric patients. Hyponatremia, hypokalemia, hypercalcaemia are clinical conditions which were present in patients of psychiatric disorders. Present study concludes that Careful evaluation of the patient will be helpful in Correction of underlying electrolyte abnormality which may improve the psychiatric symptoms and helpful for clinician for further treatment.