The Role of Vitamin D3 in Skin Pigments

The relationship of Vitamin D3 deficiency and increased melanin production that leads to appearances of facial pigments such as melasma, unevenness and hyper pigmented patches. Sample size was 28 individuals, the study was comparative study. Group A was 9 individuals with real Vitamin D3 deficiency < 12 ng/ml according to WHO definition, group B was 13 individuals which normal Vitamin D3 level, 6 individuals didn’t complete the study. The study lasts for 5 months from May to October 2019. Follow up visits on regular baseline, one after 3 weeks, one after another 3 weeks and the last visits after completion the 12 weeks. The results of a response to the current study showed that the response rate to Vitamin D therapy was very good compared to the rest of the subjects and for all groups. Where the non-response rate was zero, and the poor response rate was from 10 %, then above, the average response rate was from 50 % to 60 %, while the good rate was from 60 % to 70 %, while the highest response rate was from 80 % and above and in the figure 1 explains the difference between before and after treatment. Investigation had been done. It concluded that Vitamin D3 has an effect on improving and treating skin pigments.